SNP Detail For rs77455689
1.Mapping Information
Human SNP ID rs77455689
Human chromosome chr2
Human SNP position 141257677
Pig chromosome chr15
Pig SNP position 11406579
2.Annotation Information
PubMed ID26053186
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26053186
StudyMercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
Disease/Trait3-hydroxypropylmercapturic acid levels in smokers
Initial sample362 African American current smoker individuals, 329 Native Hawaiian ancestry current smoker individuals, 438 European ancestry current smoker individuals, 449 Latino current smoker individuals, 704 Japanese ancestry current smoker individuals
Replication sampleNA
Region2q22.1
Chromosome idchr2
Chromosome position141257677
Reported geneNR
Mapped geneLRP1B
Upstream gene id
Downstream gene id
SNP gene ids53353
Upstream gene distance
Downstream gene distance
SNP risk allelers77455689-?
SNPsrs77455689
Merged
SNP id current77455689
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000004
Pvalue mlog5.39794000867203
P value text(Native Hawaiian)
Or beta1.1204
%95 Ci[NR] unit increase
PlatformIllumina [up to 11892802] (imputed)
CNVN
Mapped traitsmoking behavior, 3-hydroxypropylmercapturic acid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004318, http://www.ebi.ac.uk/efo/EFO_0007014
Study accessionGCST002956