Human SNP ID | rs7741021 |
---|---|
Human chromosome | chr6 |
Human SNP position | 127147129 |
Pig chromosome | chr1 |
Pig SNP position | 39755696 |
PubMed ID | 24430505 |
---|---|
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24430505 |
Study | Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. |
Disease/Trait | Bone properties (heel) |
Initial sample | 4,556 European ancestry individuals |
Replication sample | 2,236 European ancestry individuals |
Region | 6q22.33 |
Chromosome id | chr6 |
Chromosome position | 127147129 |
Reported gene | RSPO3 |
Mapped gene | RSPO3, LOC105377988 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 84870, 105377988 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7741021-? |
SNPs | rs7741021 |
Merged | 0 |
SNP id current | 7741021 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | |
P value | 0.00000004 |
Pvalue mlog | 7.39794000867203 |
P value text | (BMD-DXA) |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [up to 2399195] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST002334 |
PubMed ID | 24430505 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24430505 |
Study | Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. |
Disease/Trait | Bone properties (heel) |
Initial sample | 730 East Asian ancestry individuals, 2,380 European ancestry individuals, 11,150 individuals |
Replication sample | 11,058 European ancestry individuals, 2,870 European and other ancestry individuals, 21,439 individuals |
Region | 6q22.33 |
Chromosome id | chr6 |
Chromosome position | 127147129 |
Reported gene | RSPO3 |
Mapped gene | RSPO3, LOC105377988 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 84870, 105377988 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7741021-C |
SNPs | rs7741021 |
Merged | 0 |
SNP id current | 7741021 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 9E-21 |
Pvalue mlog | 20.0457574905606 |
P value text | (BUA) |
Or beta | 0.06 |
%95 Ci | [0.05-0.07] unit increase |
Platform | Affymetrix, Illumina [up to 2609590] (imputed) |
CNV | N |
Mapped trait | bone quantitative ultrasound measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004514 |
Study accession | GCST002335 |
PubMed ID | 24430505 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24430505 |
Study | Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. |
Disease/Trait | Bone properties (heel) |
Initial sample | 2,483 East Asian ancestry individuals, 1,885 European ancestry individuals, 11,146 individuals |
Replication sample | 10,074 European ancestry individuals, 2,870 European and other ancestry individuals, 21,434 individuals |
Region | 6q22.33 |
Chromosome id | chr6 |
Chromosome position | 127147129 |
Reported gene | RSPO3 |
Mapped gene | RSPO3, LOC105377988 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 84870, 105377988 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7741021-C |
SNPs | rs7741021 |
Merged | 0 |
SNP id current | 7741021 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 1E-19 |
Pvalue mlog | 19 |
P value text | (VOS) |
Or beta | 0.06 |
%95 Ci | [0.05-0.08] unit increase |
Platform | Affymetrix, Illumina [up to 2609590] (imputed) |
CNV | N |
Mapped trait | velocity of sound measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005654 |
Study accession | GCST002333 |