Human SNP ID | rs7731626 |
---|---|
Human chromosome | chr5 |
Human SNP position | 56148856 |
Pig chromosome | chr16 |
Pig SNP position | 37353103 |
PubMed ID | 24390342 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/24390342 |
Study | Genetics of rheumatoid arthritis contributes to biology and drug discovery. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | up to 14,361 European ancestry cases, up to 42,923 European ancestry controls, up to 4,873 East Asian ancestry cases, up to 17,642 East Asian ancestry controls |
Replication sample | up to 3,775 European ancestry cases, up to 5,801 European ancestry controls, up to 6,871 East Asian ancestry cases, up to 6,392 East Asian ancestry controls |
Region | 5q11.2 |
Chromosome id | chr5 |
Chromosome position | 56148856 |
Reported gene | ANKRD55 |
Mapped gene | ANKRD55 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 79722 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7731626-G |
SNPs | rs7731626 |
Merged | 0 |
SNP id current | 7731626 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.63 |
P value | 8E-23 |
Pvalue mlog | 22.096910013008 |
P value text | (EA) |
Or beta | 1.21 |
%95 Ci | [1.17-1.26] |
Platform | Affymetrix, Illumina [up to 9739303] (imputed) |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST002318 |
PubMed ID | 26301688 |
Journal | Nat Med |
Link | www.ncbi.nlm.nih.gov/pubmed/26301688 |
Study | Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. |
Disease/Trait | Pediatric autoimmune diseases |
Initial sample | 97 European ancestry thyroiditis cases, 107 European ancestry ankylosing spondylitis cases, 100 European ancestry psoriasis cases, 173 European ancestry celiac disease cases, 254 European ancestry systemic lupus erythematosus cases, 308 European ancestry |
Replication sample | NA |
Region | 5q11.2 |
Chromosome id | chr5 |
Chromosome position | 56148856 |
Reported gene | ANKRD55 |
Mapped gene | ANKRD55 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 79722 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7731626-A |
SNPs | rs7731626 |
Merged | 0 |
SNP id current | 7731626 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.39 |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [7347414] (imputed) |
CNV | N |
Mapped trait | autoimmune thyroid disease, type I diabetes mellitus, Common variable immunodeficiency, chronic childhood arthritis, ankylosing spondylitis, psoriasis, celiac disease, ulcerative colitis, Crohn__s disease, autoimmune disease, systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006812, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.orpha.net/ORDO/Orphanet_1572, http://www.ebi.ac.uk/efo/EFO_0002609, http://www.ebi.ac.uk/efo/EFO_0003898, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo |
Study accession | GCST003097 |