SNP Detail For rs7726354
1.Mapping Information
Human SNP ID rs7726354
Human chromosome chr5
Human SNP position 56960656
Pig chromosome chr16
Pig SNP position 38300389
2.Annotation Information
PubMed ID24493630
JournalCancer Epidemiol Biomarkers Prev
Linkwww.ncbi.nlm.nih.gov/pubmed/24493630
StudyA genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.
Disease/TraitBreast cancer (early onset)
Initial sample3,523 European ancestry young female cases, 2,702 European ancestry young female controls
Replication sample3,470 European ancestry young female cases, 5,475 European ancestry young female controls
Region5q11.2
Chromosome idchr5
Chromosome position56960656
Reported geneMAP3K1
Mapped geneMIER3 - GPBP1
Upstream gene id166968
Downstream gene id65056
SNP gene ids
Upstream gene distance8526
Downstream gene distance213193
SNP risk allelers7726354-?
SNPsrs7726354
Merged0
SNP id current7726354
Contextintron_variant
Intergenic1
Allele frequency0.06
P value0.00000000007
Pvalue mlog10.1549019599857
P value text
Or beta1.37
%95 Ci[1.24-1.50]
PlatformIllumina [1265548] (imputed)
CNVN
Mapped traitbreast carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000305
Study accessionGCST002346