SNP Detail For rs7705502
1.Mapping Information
Human SNP ID rs7705502
Human chromosome chr5
Human SNP position 173893812
Pig chromosome chr16
Pig SNP position 54872531
2.Annotation Information
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region5q35.2
Chromosome idchr5
Chromosome position173893812
Reported geneCPEB4
Mapped geneCPEB4
Upstream gene id
Downstream gene id
SNP gene ids80315
Upstream gene distance
Downstream gene distance
SNP risk allelers7705502-A
SNPsrs7705502
Merged0
SNP id current7705502
Contextintron_variant
Intergenic0
Allele frequency0.324
P value0.00000002
Pvalue mlog7.69897000433601
P value text(EA, women)
Or beta0.0269
%95 Ci[0.017-0.036] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region5q35.2
Chromosome idchr5
Chromosome position173893812
Reported geneCPEB4
Mapped geneCPEB4
Upstream gene id
Downstream gene id
SNP gene ids80315
Upstream gene distance
Downstream gene distance
SNP risk allelers7705502-A
SNPsrs7705502
Merged0
SNP id current7705502
Contextintron_variant
Intergenic0
Allele frequency0.3309
P value0.0000002
Pvalue mlog6.69897000433601
P value text(EA, men)
Or beta0.0269
%95 Ci[0.017-0.037] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region5q35.2
Chromosome idchr5
Chromosome position173893812
Reported geneCPEB4
Mapped geneCPEB4
Upstream gene id
Downstream gene id
SNP gene ids80315
Upstream gene distance
Downstream gene distance
SNP risk allelers7705502-A
SNPsrs7705502
Merged0
SNP id current7705502
Contextintron_variant
Intergenic0
Allele frequency0.3278
P value0.00000000000005
Pvalue mlog13.3010299956639
P value text(EA)
Or beta0.0271
%95 Ci[0.02-0.034] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region5q35.2
Chromosome idchr5
Chromosome position173893812
Reported geneCPEB4
Mapped geneCPEB4
Upstream gene id
Downstream gene id
SNP gene ids80315
Upstream gene distance
Downstream gene distance
SNP risk allelers7705502-A
SNPsrs7705502
Merged0
SNP id current7705502
Contextintron_variant
Intergenic0
Allele frequency0.3263
P value0.0000004
Pvalue mlog6.39794000867203
P value text(men)
Or beta0.0259
%95 Ci[0.016-0.036] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region5q35.2
Chromosome idchr5
Chromosome position173893812
Reported geneCPEB4
Mapped geneCPEB4
Upstream gene id
Downstream gene id
SNP gene ids80315
Upstream gene distance
Downstream gene distance
SNP risk allelers7705502-A
SNPsrs7705502
Merged0
SNP id current7705502
Contextintron_variant
Intergenic0
Allele frequency0.3197
P value0.00000003
Pvalue mlog7.52287874528033
P value text(women)
Or beta0.0265
%95 Ci[0.017-0.036] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region5q35.2
Chromosome idchr5
Chromosome position173893812
Reported geneCPEB4
Mapped geneCPEB4
Upstream gene id
Downstream gene id
SNP gene ids80315
Upstream gene distance
Downstream gene distance
SNP risk allelers7705502-A
SNPsrs7705502
Merged0
SNP id current7705502
Contextintron_variant
Intergenic0
Allele frequency0.3223
P value0.0000000000002
Pvalue mlog12.698970004336
P value text
Or beta0.0263
%95 Ci[0.019-0.033] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782