SNP Detail For rs7677751
1.Mapping Information
Human SNP ID rs7677751
Human chromosome chr4
Human SNP position 54258293
Pig chromosome chr8
Pig SNP position 43017397
2.Annotation Information
PubMed ID22144915
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22144915
StudyGenome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.
Disease/TraitCorneal astigmatism
Initial sample1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls
Replication sample825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios
Region4q12
Chromosome idchr4
Chromosome position54258293
Reported genePDGFRA
Mapped genePDGFRA
Upstream gene id
Downstream gene id
SNP gene ids5156
Upstream gene distance
Downstream gene distance
SNP risk allelers7677751-T
SNPsrs7677751
Merged0
SNP id current7677751
Contextintron_variant
Intergenic0
Allele frequency0.22
P value0.000000008
Pvalue mlog8.09691001300805
P value text
Or beta1.26
%95 Ci[1.18-1.34]
PlatformIllumina [460528]
CNVN
Mapped traitAstigmatism
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0000483
Study accessionGCST001339