Human SNP ID | rs7677751 |
---|---|
Human chromosome | chr4 |
Human SNP position | 54258293 |
Pig chromosome | chr8 |
Pig SNP position | 43017397 |
PubMed ID | 22144915 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22144915 |
Study | Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. |
Disease/Trait | Corneal astigmatism |
Initial sample | 1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls |
Replication sample | 825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios |
Region | 4q12 |
Chromosome id | chr4 |
Chromosome position | 54258293 |
Reported gene | PDGFRA |
Mapped gene | PDGFRA |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 5156 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7677751-T |
SNPs | rs7677751 |
Merged | 0 |
SNP id current | 7677751 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.22 |
P value | 0.000000008 |
Pvalue mlog | 8.09691001300805 |
P value text | |
Or beta | 1.26 |
%95 Ci | [1.18-1.34] |
Platform | Illumina [460528] |
CNV | N |
Mapped trait | Astigmatism |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0000483 |
Study accession | GCST001339 |