Human SNP ID | rs7671167 |
---|---|
Human chromosome | chr4 |
Human SNP position | 88962828 |
Pig chromosome | chr8 |
Pig SNP position | 139556439 |
PubMed ID | 20173748 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20173748 |
Study | Variants in FAM13A are associated with chronic obstructive pulmonary disease. |
Disease/Trait | Chronic obstructive pulmonary disease |
Initial sample | 2,940 European ancestry cases, 1,380 European ancestry controls |
Replication sample | 502 European ancestry cases, 504 European ancestry controls, 1,110 cases, 2,698 controls |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 88962828 |
Reported gene | FAM13A |
Mapped gene | FAM13A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10144 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7671167-? |
SNPs | rs7671167 |
Merged | 0 |
SNP id current | 7671167 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.48 |
P value | 0.00000000001 |
Pvalue mlog | 11 |
P value text | |
Or beta | 1.32 |
%95 Ci | [1.19-1.47] |
Platform | Illumina [499578] |
CNV | N |
Mapped trait | chronic obstructive pulmonary disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000341 |
Study accession | GCST000603 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1 |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 88962828 |
Reported gene | FAM13A |
Mapped gene | FAM13A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10144 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7671167-T |
SNPs | rs7671167 |
Merged | 0 |
SNP id current | 7671167 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.468 |
P value | 0.00000009 |
Pvalue mlog | 7.04575749056067 |
P value text | |
Or beta | 0.046 |
%95 Ci | NR unit decrease |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | forced expiratory volume, response to bronchodilator |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366 |
Study accession | GCST003262 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1/FVC ratio |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 88962828 |
Reported gene | FAM13A |
Mapped gene | FAM13A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 10144 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7671167-T |
SNPs | rs7671167 |
Merged | 0 |
SNP id current | 7671167 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.467 |
P value | 0.0000000002 |
Pvalue mlog | 9.69897000433601 |
P value text | |
Or beta | 0.011 |
%95 Ci | unit decrease |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | response to bronchodilator, FEV/FEC ratio |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST003264 |