SNP Detail For rs76495833
1.Mapping Information
Human SNP ID rs76495833
Human chromosome chr3
Human SNP position 30627911
Pig chromosome chr13
Pig SNP position 18676663
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCognitive decline rate in late mild cognitive impairment
Initial sample472 European ancestry cases, 47 cases
Replication sampleNA
Region3p24.1
Chromosome idchr3
Chromosome position30627911
Reported geneTGFBR2
Mapped geneTGFBR2
Upstream gene id
Downstream gene id
SNP gene ids7048
Upstream gene distance
Downstream gene distance
SNP risk allelers76495833-C
SNPsrs76495833
Merged
SNP id current76495833
Contextintron_variant
Intergenic0
Allele frequency0.04
P value0.00000008
Pvalue mlog7.09691001300805
P value text(EA)
Or beta0.4484
%95 Ci[0.29-0.61] unit increase
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcognitive impairment, cognitive decline measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0100543, http://www.ebi.ac.uk/efo/EFO_0007710
Study accessionGCST003075
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCognitive decline rate in late mild cognitive impairment
Initial sample472 European ancestry cases, 47 cases
Replication sampleNA
Region3p24.1
Chromosome idchr3
Chromosome position30627911
Reported geneTGFBR2
Mapped geneTGFBR2
Upstream gene id
Downstream gene id
SNP gene ids7048
Upstream gene distance
Downstream gene distance
SNP risk allelers76495833-C
SNPsrs76495833
Merged
SNP id current76495833
Contextintron_variant
Intergenic0
Allele frequency0.04
P value0.000001
Pvalue mlog6
P value text
Or beta0.3689
%95 Ci[0.22-0.52] unit increase
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcognitive impairment, cognitive decline measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0100543, http://www.ebi.ac.uk/efo/EFO_0007710
Study accessionGCST003075