SNP Detail For rs7620503
1.Mapping Information
Human SNP ID rs7620503
Human chromosome chr3
Human SNP position 177586510
Pig chromosome chr13
Pig SNP position 124909470
2.Annotation Information
PubMed ID23291589
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23291589
StudyGenome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
Disease/TraitCorneal structure
Initial sample13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals
Replication sampleNA
Region3q26.32
Chromosome idchr3
Chromosome position177586510
Reported geneTBL1XR1, KCNMB2
Mapped geneLINC00578, LOC105374232
Upstream gene id
Downstream gene id
SNP gene ids100505566, 105374232
Upstream gene distance
Downstream gene distance
SNP risk allelers7620503-T
SNPsrs7620503
Merged0
SNP id current7620503
Contextintron_variant
Intergenic0
Allele frequency0.39
P value0.00000001
Pvalue mlog8
P value text
Or beta0.06
%95 Ci[0.04-0.08] unit decrease
PlatformAffymetrix, Illumina [~ 1000000] (imputed)
CNVN
Mapped traitcorneal topography
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004345
Study accessionGCST001806