Human SNP ID | rs7617480 |
---|---|
Human chromosome | chr3 |
Human SNP position | 49173299 |
Pig chromosome | chr13 |
Pig SNP position | 35007939 |
PubMed ID | 21102462 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21102462 |
Study | Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. |
Disease/Trait | Menarche (age at onset) |
Initial sample | 86,142 European ancestry female individuals, 557 Old Order Amish female individuals, 1,103 Erasmus Rucphen female individuals |
Replication sample | Up to 12,813 European ancestry female individuals, 910 Val Borbera female individuals, 348 Orcadian female individuals, 338 Friuli Venezia Giulia female individuals, 322 Carlantino female individuals |
Region | 3p21.31 |
Chromosome id | chr3 |
Chromosome position | 49173299 |
Reported gene | KLHDC8B |
Mapped gene | KLHDC8B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 200942 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7617480-A |
SNPs | rs7617480 |
Merged | 0 |
SNP id current | 7617480 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.22 |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | |
Or beta | 2.4 |
%95 Ci | [1.62-3.18] week decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | age at menarche |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004703 |
Study accession | GCST000880 |