SNP Detail For rs76137255
1.Mapping Information
Human SNP ID rs76137255
Human chromosome chr19
Human SNP position 40277925
Pig chromosome chr6
Pig SNP position 44370110
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCerebrospinal T-tau levels
Initial sampleup to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer__s disease cases, up to 215 European and other ance
Replication sampleup to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other an
Region19q13.2
Chromosome idchr19
Chromosome position40277925
Reported geneAKT2
Mapped geneAKT2
Upstream gene id
Downstream gene id
SNP gene ids208
Upstream gene distance
Downstream gene distance
SNP risk allelers76137255-T
SNPsrs76137255
Merged
SNP id current76137255
Contextintron_variant
Intergenic0
Allele frequency0.02
P value0.0000002
Pvalue mlog6.69897000433601
P value text
Or beta0.3236
%95 Ci[NR] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitcerebrospinal fluid biomarker measurement, t-tau measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006794, http://www.ebi.ac.uk/efo/EFO_0004760
Study accessionGCST003070
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCerebrospinal fluid t-tau:AB1-42 ratio
Initial sampleup to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer__s disease cases, up to 215 European and other ance
Replication sampleup to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other an
Region19q13.2
Chromosome idchr19
Chromosome position40277925
Reported geneAKT2
Mapped geneAKT2
Upstream gene id
Downstream gene id
SNP gene ids208
Upstream gene distance
Downstream gene distance
SNP risk allelers76137255-T
SNPsrs76137255
Merged
SNP id current76137255
Contextintron_variant
Intergenic0
Allele frequency0.02
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta0.3749
%95 Ci[NR] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitt-tau:beta-amyloid 1-42 ratio measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0007708
Study accessionGCST003079