SNP Detail For rs7604423
1.Mapping Information
Human SNP ID rs7604423
Human chromosome chr2
Human SNP position 43155602
Pig chromosome chr3
Pig SNP position 103321247
2.Annotation Information
PubMed ID26390057
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26390057
StudyTrans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Disease/TraitDiastolic blood pressure
Initial sample31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals
Replication sample87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals, 16,328 South Asian ancestry individuals
Region2p21
Chromosome idchr2
Chromosome position43155602
Reported geneNR
Mapped geneLOC100506047
Upstream gene id
Downstream gene id
SNP gene ids100506047
Upstream gene distance
Downstream gene distance
SNP risk allelers7604423-C
SNPsrs7604423
Merged
SNP id current7604423
Contextregulatory_region_variant
Intergenic0
Allele frequency0.659961723
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta0.2093915
%95 Ci[0.14-0.28] mmHg decrease
PlatformAffymetrix, Illumina, Perlegen [~ 2100000] (imputed)
CNVN
Mapped traitdiastolic blood pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006336
Study accessionGCST003273