Human SNP ID | rs7604423 |
---|---|
Human chromosome | chr2 |
Human SNP position | 43155602 |
Pig chromosome | chr3 |
Pig SNP position | 103321247 |
PubMed ID | 26390057 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26390057 |
Study | Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. |
Disease/Trait | Diastolic blood pressure |
Initial sample | 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals |
Replication sample | 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals, 16,328 South Asian ancestry individuals |
Region | 2p21 |
Chromosome id | chr2 |
Chromosome position | 43155602 |
Reported gene | NR |
Mapped gene | LOC100506047 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 100506047 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7604423-C |
SNPs | rs7604423 |
Merged | |
SNP id current | 7604423 |
Context | regulatory_region_variant |
Intergenic | 0 |
Allele frequency | 0.659961723 |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 0.2093915 |
%95 Ci | [0.14-0.28] mmHg decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) |
CNV | N |
Mapped trait | diastolic blood pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006336 |
Study accession | GCST003273 |