Human SNP ID | rs7582701 |
---|---|
Human chromosome | chr2 |
Human SNP position | 46323630 |
Pig chromosome | chr3 |
Pig SNP position | 100308327 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 2p21 |
Chromosome id | chr2 |
Chromosome position | 46323630 |
Reported gene | NR |
Mapped gene | LOC105374583, EPAS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105374583, 2034 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7582701-C |
SNPs | rs7582701 |
Merged | 0 |
SNP id current | 7582701 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0373370440481498 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | (IGP69) |
Or beta | 0.4547 |
%95 Ci | [0.27-0.64] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 2p21 |
Chromosome id | chr2 |
Chromosome position | 46323630 |
Reported gene | NR |
Mapped gene | LOC105374583, EPAS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105374583, 2034 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7582701-C |
SNPs | rs7582701 |
Merged | 0 |
SNP id current | 7582701 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.037394344593387 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (IGP74) |
Or beta | 0.4338 |
%95 Ci | [0.25-0.62] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 2p21 |
Chromosome id | chr2 |
Chromosome position | 46323630 |
Reported gene | NR |
Mapped gene | LOC105374583, EPAS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105374583, 2034 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7582701-C |
SNPs | rs7582701 |
Merged | 0 |
SNP id current | 7582701 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0373185578689255 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP75) |
Or beta | 0.4488 |
%95 Ci | [0.27-0.63] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 2p21 |
Chromosome id | chr2 |
Chromosome position | 46323630 |
Reported gene | NR |
Mapped gene | LOC105374583, EPAS1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105374583, 2034 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7582701-C |
SNPs | rs7582701 |
Merged | 0 |
SNP id current | 7582701 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.0372783807743658 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (IGP76) |
Or beta | 0.4309 |
%95 Ci | [0.25-0.61] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |