Human SNP ID | rs7555523 |
---|---|
Human chromosome | chr1 |
Human SNP position | 165749742 |
Pig chromosome | chr4 |
Pig SNP position | 92640116 |
PubMed ID | 22570627 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22570627 |
Study | Common genetic determinants of intraocular pressure and primary open-angle glaucoma. |
Disease/Trait | Intraocular pressure |
Initial sample | 11,972 European ancestry individuals |
Replication sample | 7,482 European ancestry individuals |
Region | 1q24.1 |
Chromosome id | chr1 |
Chromosome position | 165749742 |
Reported gene | TMCO1 |
Mapped gene | TMCO1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54499 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7555523-C |
SNPs | rs7555523 |
Merged | 0 |
SNP id current | 7555523 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.12 |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 0.28 |
%95 Ci | [0.18-0.37] mmHg increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | intraocular pressure measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004695 |
Study accession | GCST001506 |
PubMed ID | 25173106 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25173106 |
Study | Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. |
Disease/Trait | Intraocular pressure |
Initial sample | 7,738 Asian ancestry individuals, 27,558 European ancestry individuals |
Replication sample | NA |
Region | 1q24.1 |
Chromosome id | chr1 |
Chromosome position | 165749742 |
Reported gene | TMCO1 |
Mapped gene | TMCO1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 54499 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7555523-C |
SNPs | rs7555523 |
Merged | 0 |
SNP id current | 7555523 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | |
Or beta | 0.235 |
%95 Ci | [0.16-0.31] mm Hg increase |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | intraocular pressure measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004695 |
Study accession | GCST002580 |