SNP Detail For rs7554182
1.Mapping Information
Human SNP ID rs7554182
Human chromosome chr1
Human SNP position 182052148
Pig chromosome chr9
Pig SNP position 135663200
2.Annotation Information
PubMed ID24554482
JournalJ Neurovirol
Linkwww.ncbi.nlm.nih.gov/pubmed/24554482
StudyGenome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
Disease/TraitResponse to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy)
Initial sample8 European ancestry cases, 12 African American cases, 3 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls
Replication sampleNA
Region1q25.3
Chromosome idchr1
Chromosome position182052148
Reported geneZNF648
Mapped geneLOC105371640 - ZNF648
Upstream gene id105371640
Downstream gene id127665
SNP gene ids
Upstream gene distance47818
Downstream gene distance1618
SNP risk allelers7554182-?
SNPsrs7554182
Merged0
SNP id current7554182
Contextdownstream_gene_variant
Intergenic1
Allele frequency
P value0.00000006
Pvalue mlog7.22184874961635
P value text(AA)
Or beta48.5
%95 Ci[NR]
PlatformIllumina [936149]
CNVN
Mapped traitresponse to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100
Study accessionGCST002363