Human SNP ID | rs7553007 |
---|---|
Human chromosome | chr1 |
Human SNP position | 159728759 |
Pig chromosome | chr4 |
Pig SNP position | 98737937 |
PubMed ID | 19567438 |
---|---|
Journal | JAMA |
Link | www.ncbi.nlm.nih.gov/pubmed/19567438 |
Study | Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. |
Disease/Trait | C-reactive protein |
Initial sample | 17,967 European ancestry and Indian Asian ancestry individuals |
Replication sample | 13,615 European ancestry and Indian Asian ancestry Individuals |
Region | 1q23.2 |
Chromosome id | chr1 |
Chromosome position | 159728759 |
Reported gene | CRP |
Mapped gene | CRP - RPL27P2 |
Upstream gene id | 1401 |
Downstream gene id | 646446 |
SNP gene ids | |
Upstream gene distance | 14150 |
Downstream gene distance | 30385 |
SNP risk allele | rs7553007-A |
SNPs | rs7553007 |
Merged | 0 |
SNP id current | 7553007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 8E-44 |
Pvalue mlog | 43.096910013008 |
P value text | |
Or beta | 20.7 |
%95 Ci | [18.9-23.4] % decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 1400000] (imputed) |
CNV | N |
Mapped trait | C-reactive protein measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004458 |
Study accession | GCST000430 |
PubMed ID | 22939635 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22939635 |
Study | Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. |
Disease/Trait | C-reactive protein |
Initial sample | 8,280 African American female individuals, 3,548 Hispanic female individuals |
Replication sample | 3,787 African American female individuals, 3,548 Hispanic female individuals, 5,656 European ancestry individuals |
Region | 1q23.2 |
Chromosome id | chr1 |
Chromosome position | 159728759 |
Reported gene | CRP |
Mapped gene | CRP - RPL27P2 |
Upstream gene id | 1401 |
Downstream gene id | 646446 |
SNP gene ids | |
Upstream gene distance | 14150 |
Downstream gene distance | 30385 |
SNP risk allele | rs7553007-G |
SNPs | rs7553007 |
Merged | 0 |
SNP id current | 7553007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.344 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | (HA women) |
Or beta | 0.129 |
%95 Ci | [0.078-0.180] unit increase |
Platform | Affymetrix [up to 2203609] (imputed) |
CNV | N |
Mapped trait | C-reactive protein measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004458 |
Study accession | GCST001650 |
PubMed ID | 22939635 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22939635 |
Study | Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. |
Disease/Trait | C-reactive protein |
Initial sample | 8,280 African American female individuals, 3,548 Hispanic female individuals |
Replication sample | 3,787 African American female individuals, 3,548 Hispanic female individuals, 5,656 European ancestry individuals |
Region | 1q23.2 |
Chromosome id | chr1 |
Chromosome position | 159728759 |
Reported gene | FCER1A, DUSP23, OR10J1, APCS, DARC, IFI16, OR10J5, CRP, OR10J3, OLFML2B, FCRL6 |
Mapped gene | CRP - RPL27P2 |
Upstream gene id | 1401 |
Downstream gene id | 646446 |
SNP gene ids | |
Upstream gene distance | 14150 |
Downstream gene distance | 30385 |
SNP risk allele | rs7553007-T |
SNPs | rs7553007 |
Merged | 0 |
SNP id current | 7553007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.228 |
P value | 1E-37 |
Pvalue mlog | 37 |
P value text | (AA women) |
Or beta | 0.272 |
%95 Ci | [0.23-0.31] unit decrease |
Platform | Affymetrix [up to 2203609] (imputed) |
CNV | N |
Mapped trait | C-reactive protein measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004458 |
Study accession | GCST001650 |
PubMed ID | 24763700 |
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/24763700 |
Study | New variants including ARG1 polymorphisms associated with C-reactive protein levels identified by genome-wide association and pathway analysis. |
Disease/Trait | C-reactive protein levels |
Initial sample | 7,626 Korean ancestry individuals |
Replication sample | 903 Korean ancestry individuals |
Region | 1q23.2 |
Chromosome id | chr1 |
Chromosome position | 159728759 |
Reported gene | CRP |
Mapped gene | CRP - RPL27P2 |
Upstream gene id | 1401 |
Downstream gene id | 646446 |
SNP gene ids | |
Upstream gene distance | 14150 |
Downstream gene distance | 30385 |
SNP risk allele | rs7553007-C |
SNPs | rs7553007 |
Merged | 0 |
SNP id current | 7553007 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.369 |
P value | 0.0000000000000002 |
Pvalue mlog | 15.698970004336 |
P value text | |
Or beta | 0.164 |
%95 Ci | [NR] unit increase |
Platform | Affymetrix [1219546] (imputed) |
CNV | N |
Mapped trait | C-reactive protein measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004458 |
Study accession | GCST002424 |