SNP Detail For rs7545447
1.Mapping Information
Human SNP ID rs7545447
Human chromosome chr1
Human SNP position 218510675
Pig chromosome chr10
Pig SNP position 10411584
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position218510675
Reported geneIntergenic
Mapped geneTGFB2 - LOC105372924
Upstream gene id7042
Downstream gene id105372924
SNP gene ids
Upstream gene distance66056
Downstream gene distance187889
SNP risk allelers7545447-A
SNPsrs7545447
Merged0
SNP id current7545447
Contextintron_variant
Intergenic1
Allele frequency0.169
P value0.000001
Pvalue mlog6
P value text
Or beta0.012
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264