SNP Detail For rs7536700
1.Mapping Information
Human SNP ID rs7536700
Human chromosome chr1
Human SNP position 153668351
Pig chromosome chr4
Pig SNP position 104875818
2.Annotation Information
PubMed ID23502783
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23502783
StudyThe CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Disease/TraitMultiple myeloma (IgH translocation)
Initial sampleup to 1,660 European ancestry cases, 7,306 European ancestry controls
Replication sample
Region1q21.3
Chromosome idchr1
Chromosome position153668351
Reported geneNR
Mapped geneILF2
Upstream gene id
Downstream gene id
SNP gene ids3608
Upstream gene distance
Downstream gene distance
SNP risk allelers7536700-A
SNPsrs7536700
Merged0
SNP id current7536700
Contextintron_variant
Intergenic0
Allele frequency0.07
P value0.000004
Pvalue mlog5.39794000867203
P value text(Any IgH translocation vs. controls)
Or beta1.53
%95 Ci[1.28-1.84]
PlatformIllumina [414804] (imputed)
CNVN
Mapped traitmultiple myeloma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001378
Study accessionGCST001906
PubMed ID23502783
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23502783
StudyThe CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Disease/TraitMultiple myeloma (IgH translocation)
Initial sampleup to 1,660 European ancestry cases, 7,306 European ancestry controls
Replication sample
Region1q21.3
Chromosome idchr1
Chromosome position153668351
Reported geneNR
Mapped geneILF2
Upstream gene id
Downstream gene id
SNP gene ids3608
Upstream gene distance
Downstream gene distance
SNP risk allelers7536700-A
SNPsrs7536700
Merged0
SNP id current7536700
Contextintron_variant
Intergenic0
Allele frequency0.07
P value0.000009
Pvalue mlog5.04575749056067
P value text(non t11;14 and t4;14 IgH translocations vs. controls)
Or beta1.86
%95 Ci[1.42-2.46]
PlatformIllumina [414804] (imputed)
CNVN
Mapped traitmultiple myeloma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001378
Study accessionGCST001906