Human SNP ID | rs7521902 |
---|---|
Human chromosome | chr1 |
Human SNP position | 22164231 |
Pig chromosome | chr6 |
Pig SNP position | 74185808 |
PubMed ID | 20852632 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20852632 |
Study | A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. |
Disease/Trait | Ovarian cancer |
Initial sample | 1,768 European ancestry cases, 2,354 European ancestry controls |
Replication sample | 8,709 European ancestry cases, 51,764 European ancestry controls |
Region | 1p36.12 |
Chromosome id | chr1 |
Chromosome position | 22164231 |
Reported gene | NR |
Mapped gene | LOC105376850 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105376850 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7521902-? |
SNPs | rs7521902 |
Merged | 0 |
SNP id current | 7521902 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | |
Or beta | 1.12 |
%95 Ci | [1.07-1.18] |
Platform | Illumina [2056878] (imputed) |
CNV | N |
Mapped trait | ovarian carcinoma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001075 |
Study accession | GCST000802 |
PubMed ID | 22504420 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22504420 |
Study | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. |
Disease/Trait | Bone mineral density |
Initial sample | Up to 32,961 European and East Asian ancestry individuals |
Replication sample | Up to 50,933 European and East Asian ancestry individuals |
Region | 1p36.12 |
Chromosome id | chr1 |
Chromosome position | 22164231 |
Reported gene | WNT4 |
Mapped gene | LOC105376850 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105376850 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7521902-A |
SNPs | rs7521902 |
Merged | 0 |
SNP id current | 7521902 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.31 |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | (LSBMD) |
Or beta | 0.05 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST001482 |
PubMed ID | 23104006 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23104006 |
Study | Genome-wide association meta-analysis identifies new endometriosis risk loci. |
Disease/Trait | Endometriosis |
Initial sample | 3,181 European ancestry cases, 8,075 European ancestry controls, 1,423 Japanese ancestry cases, 1,318 Japanese ancestry controls |
Replication sample | 1,044 Japanese ancestry, 4,017 Japanese ancestry controls |
Region | 1p36.12 |
Chromosome id | chr1 |
Chromosome position | 22164231 |
Reported gene | WNT4 |
Mapped gene | LOC105376850 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105376850 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7521902-A |
SNPs | rs7521902 |
Merged | 0 |
SNP id current | 7521902 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.238 |
P value | 0.00000000003 |
Pvalue mlog | 10.5228787452803 |
P value text | |
Or beta | 1.19 |
%95 Ci | [1.13-1.25] |
Platform | Illumina [407632] |
CNV | N |
Mapped trait | endometriosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001065 |
Study accession | GCST001720 |
PubMed ID | 23472165 |
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/23472165 |
Study | Genome-wide association study link novel loci to endometriosis. |
Disease/Trait | Endometriosis |
Initial sample | 1,514 European ancestry casses, 12,660 European ancestry controls |
Replication sample | 505 European ancestry cases, 1,811 European ancestry controls |
Region | 1p36.12 |
Chromosome id | chr1;1;1;1;1 |
Chromosome position | 22096228;22164231;22113027;22123994;22159378 |
Reported gene | WNT4 |
Mapped gene | CDC42 - WNT4; LOC105376850; CDC42 - WNT4; WNT4; LOC105376845 - LOC105376850 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10917151-A; rs7521902-A; rs4654783-T; rs2235529-T; rs16826658-G |
SNPs | rs10917151; rs7521902; rs4654783; rs2235529; rs16826658 |
Merged | 0 |
SNP id current | |
Context | upstream_gene_variant; intergenic_variant; downstream_gene_variant; intron_variant; intergenic_variant |
Intergenic | |
Allele frequency | 0.134 |
P value | 0.0000008 |
Pvalue mlog | 6.09691001300805 |
P value text | |
Or beta | 1.25 |
%95 Ci | [NR] |
Platform | Illumina [580699] |
CNV | N |
Mapped trait | endometriosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001065 |
Study accession | GCST001894 |