SNP Detail For rs7512552
1.Mapping Information
Human SNP ID rs7512552
Human chromosome chr1
Human SNP position 150293284
Pig chromosome chr4
Pig SNP position 108083180
2.Annotation Information
PubMed ID26482879
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26482879
StudyMulti-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Disease/TraitAtopic dermatitis
Initial sample18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls
Replication sample30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls
Region1q21.2
Chromosome idchr1
Chromosome position150293284
Reported geneC1orf51, MRPS21
Mapped geneCIART - LOC105371434
Upstream gene id148523
Downstream gene id105371434
SNP gene ids
Upstream gene distance6191
Downstream gene distance18
SNP risk allelers7512552-C
SNPsrs7512552
Merged0
SNP id current7512552
Contextupstream_gene_variant
Intergenic1
Allele frequency0.51
P value0.000000005
Pvalue mlog8.30102999566398
P value text(EA, fixed effects)
Or beta1.0416667
%95 Ci
PlatformIllumina [15539996] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST003184
PubMed ID26482879
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26482879
StudyMulti-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.
Disease/TraitAtopic dermatitis
Initial sample18,900 European ancestry cases, 1,472 Japanese ancestry cases, 422 African American cases, 300 Latino cases, 305 cases, 84,166 European ancestry controls, 7,966 Japanese ancestry controls, 844 African American controls, 1,592 Latino controls, 896 controls
Replication sample30,588 European ancestry cases, 459 African American cases, 1,012 Chinese ancestry cases, 226,537 European ancestry controls, 729 African American controls, 1,362 Chinese ancestry controls
Region1q21.2
Chromosome idchr1
Chromosome position150293284
Reported geneC1orf51, MRPS21
Mapped geneCIART - LOC105371434
Upstream gene id148523
Downstream gene id105371434
SNP gene ids
Upstream gene distance6191
Downstream gene distance18
SNP risk allelers7512552-T
SNPsrs7512552
Merged0
SNP id current7512552
Contextupstream_gene_variant
Intergenic1
Allele frequency0.49
P value0.0000001
Pvalue mlog7
P value text(random effects)
Or beta
%95 CiNR
PlatformIllumina [15539996] (imputed)
CNVN
Mapped traitatopic eczema
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000274
Study accessionGCST003184