SNP Detail For rs74888189
1.Mapping Information
Human SNP ID rs74888189
Human chromosome chr11
Human SNP position 120630009
Pig chromosome chr9
Pig SNP position 52787834
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1 in COPD
Initial sample5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases
Replication sampleNA
Region11q23.3
Chromosome idchr11
Chromosome position120630009
Reported geneGRIK4
Mapped geneGRIK4
Upstream gene id
Downstream gene id
SNP gene ids2900
Upstream gene distance
Downstream gene distance
SNP risk allelers74888189-T
SNPsrs74888189
Merged0
SNP id current74888189
Contextintron_variant
Intergenic0
Allele frequency0.959
P value0.000001
Pvalue mlog6
P value text(AA)
Or beta0.331
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator, chronic obstructive pulmonary disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341
Study accessionGCST003263