SNP Detail For rs74498795
1.Mapping Information
Human SNP ID rs74498795
Human chromosome chr3
Human SNP position 46734762
Pig chromosome chr13
Pig SNP position 32913294
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3p21.31
Chromosome idchr3
Chromosome position46734762
Reported genePRSS46
Mapped genePRSS46
Upstream gene id
Downstream gene id
SNP gene ids100287362
Upstream gene distance
Downstream gene distance
SNP risk allelers74498795-G
SNPsrs74498795
Merged0
SNP id current74498795
Contextintron_variant
Intergenic0
Allele frequency0.999
P value0.0000003
Pvalue mlog6.52287874528033
P value text(AA)
Or beta0.224
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264