SNP Detail For rs73229090
1.Mapping Information
Human SNP ID rs73229090
Human chromosome chr8
Human SNP position 27584610
Pig chromosome chr14
Pig SNP position 12505085
2.Annotation Information
PubMed ID25056061
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25056061
StudyBiological insights from 108 schizophrenia-associated genetic loci.
Disease/TraitSchizophrenia
Initial sample32,405 European ancestry cases, 42,221 European ancestry controls, 1,235 European ancestry cases and 1,235 European ancestry controls from 1235 parent-offspring trios, 1,836 East Asian ancestry cases, 3,383 East Asian ancestry controls
Replication sample1,513 European ancestry cases, 66,236 European ancestry controls
Region8p21.1
Chromosome idchr8
Chromosome position27584610
Reported geneCLU, EPHX2
Mapped geneEPHX2 - LOC105379341
Upstream gene id2053
Downstream gene id105379341
SNP gene ids
Upstream gene distance39688
Downstream gene distance5501
SNP risk allelers73229090-C
SNPsrs73229090
Merged0
SNP id current73229090
Contextintron_variant
Intergenic1
Allele frequency0.884
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta1.1013216
%95 Ci[1.06-1.14]
PlatformAffymetrix, Illumina [9005918] (imputed)
CNVN
Mapped traitschizophrenia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000692
Study accessionGCST002539
PubMed ID26198764
JournalAm J Med Genet B Neuropsychiatr Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26198764
StudyGenome-wide association study of schizophrenia in Ashkenazi Jews.
Disease/TraitSchizophrenia
Initial sample592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls
Replication sampleNA
Region8p21.1
Chromosome idchr8
Chromosome position27584610
Reported geneNR
Mapped geneEPHX2 - LOC105379341
Upstream gene id2053
Downstream gene id105379341
SNP gene ids
Upstream gene distance39688
Downstream gene distance5501
SNP risk allelers73229090-C
SNPsrs73229090
Merged0
SNP id current73229090
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta1.098901
%95 Ci[NR]
PlatformIllumina [7158791] (imputed)
CNVN
Mapped traitschizophrenia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000692
Study accessionGCST003048