SNP Detail For rs73125111
1.Mapping Information
Human SNP ID rs73125111
Human chromosome chr3
Human SNP position 85061820
Pig chromosome chr13
Pig SNP position 181747004
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3p12.1
Chromosome idchr3
Chromosome position85061820
Reported geneCADM2
Mapped geneCADM2
Upstream gene id
Downstream gene id
SNP gene ids253559
Upstream gene distance
Downstream gene distance
SNP risk allelers73125111-C
SNPsrs73125111
Merged0
SNP id current73125111
Contextintron_variant
Intergenic0
Allele frequency0.98
P value0.000001
Pvalue mlog6
P value text
Or beta0.216
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3p12.1
Chromosome idchr3
Chromosome position85061820
Reported geneCADM2
Mapped geneCADM2
Upstream gene id
Downstream gene id
SNP gene ids253559
Upstream gene distance
Downstream gene distance
SNP risk allelers73125111-C
SNPsrs73125111
Merged0
SNP id current73125111
Contextintron_variant
Intergenic0
Allele frequency0.981
P value0.0000009
Pvalue mlog6.04575749056067
P value text
Or beta0.045
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264