SNP Detail For rs7312122
1.Mapping Information
Human SNP ID rs7312122
Human chromosome chr12
Human SNP position 112721033
Pig chromosome chr14
Pig SNP position 41547370
2.Annotation Information
PubMed ID19901119
JournalJ Clin Oncol
Linkwww.ncbi.nlm.nih.gov/pubmed/19901119
StudyGermline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects.
Disease/TraitMethotrexate phramacokinetics (acute lymphoblastic leukemia)
Initial sample315 European ancestry cases, 73 African American cases, 5 Asian ancestry cases, 247 cases
Replication sampleNA
Region12q24.13
Chromosome idchr12
Chromosome position112721033
Reported geneintergenic
Mapped geneMIR1302-1 - RPH3A
Upstream gene id100302227
Downstream gene id22895
SNP gene ids
Upstream gene distance25857
Downstream gene distance70505
SNP risk allelers7312122-G
SNPsrs7312122
Merged0
SNP id current7312122
Contextintron_variant
Intergenic1
Allele frequency0.16
P value0.000009
Pvalue mlog5.04575749056067
P value text
Or beta
%95 Ci[NR]
PlatformAffymetrix [398699]
CNVN
Mapped traitresponse to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST000523