Human SNP ID | rs727428 |
---|---|
Human chromosome | chr17 |
Human SNP position | 7634474 |
Pig chromosome | chr12 |
Pig SNP position | 55255279 |
PubMed ID | 22675492 |
---|---|
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/22675492 |
Study | Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women. |
Disease/Trait | Sex hormone-binding globulin levels |
Initial sample | 1,598 European ancestry female individuals |
Replication sample | NA |
Region | 17p13.1 |
Chromosome id | chr17 |
Chromosome position | 7634474 |
Reported gene | FXR2, SHBG, SAT2, ATP1B2 |
Mapped gene | SHBG - ATP1B2 |
Upstream gene id | 6462 |
Downstream gene id | 482 |
SNP gene ids | |
Upstream gene distance | 1091 |
Downstream gene distance | 12153 |
SNP risk allele | rs727428-T |
SNPs | rs727428 |
Merged | 0 |
SNP id current | 727428 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.42 |
P value | 0.0000000000000002 |
Pvalue mlog | 15.698970004336 |
P value text | |
Or beta | 0.126 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | sex hormone globulin binding measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004696 |
Study accession | GCST001554 |
PubMed ID | 22936694 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22936694 |
Study | Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men. |
Disease/Trait | Androgen levels |
Initial sample | 3,225 European ancestry male individuals |
Replication sample | NA |
Region | 17p13.1 |
Chromosome id | chr17 |
Chromosome position | 7634474 |
Reported gene | SHBG |
Mapped gene | SHBG - ATP1B2 |
Upstream gene id | 6462 |
Downstream gene id | 482 |
SNP gene ids | |
Upstream gene distance | 1091 |
Downstream gene distance | 12153 |
SNP risk allele | rs727428-T |
SNPs | rs727428 |
Merged | 0 |
SNP id current | 727428 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.414 |
P value | 0.000000000001 |
Pvalue mlog | 12 |
P value text | (serum testosterone) |
Or beta | 0.073 |
%95 Ci | [0.053-0.093] unit decrease |
Platform | Illumina [642461] |
CNV | N |
Mapped trait | testosterone measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004908 |
Study accession | GCST001653 |
PubMed ID | 22936694 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22936694 |
Study | Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men. |
Disease/Trait | Androgen levels |
Initial sample | 3,225 European ancestry male individuals |
Replication sample | NA |
Region | 17p13.1 |
Chromosome id | chr17 |
Chromosome position | 7634474 |
Reported gene | SHBG |
Mapped gene | SHBG - ATP1B2 |
Upstream gene id | 6462 |
Downstream gene id | 482 |
SNP gene ids | |
Upstream gene distance | 1091 |
Downstream gene distance | 12153 |
SNP risk allele | rs727428-T |
SNPs | rs727428 |
Merged | 0 |
SNP id current | 727428 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.414 |
P value | 0.00000000001 |
Pvalue mlog | 11 |
P value text | (DHT levels) |
Or beta | 0.103 |
%95 Ci | [0.074-0.132] unit decrease |
Platform | Illumina [642461] |
CNV | N |
Mapped trait | dihydrotestosterone measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004909 |
Study accession | GCST001653 |