SNP Detail For rs72738847
1.Mapping Information
Human SNP ID rs72738847
Human chromosome chr1
Human SNP position 218503102
Pig chromosome chr10
Pig SNP position 10407233
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position218503102
Reported geneIntergenic
Mapped geneTGFB2 - LOC105372924
Upstream gene id7042
Downstream gene id105372924
SNP gene ids
Upstream gene distance58483
Downstream gene distance195462
SNP risk allelers72738847-T
SNPsrs72738847
Merged0
SNP id current72738847
Contextintergenic_variant
Intergenic1
Allele frequency0.103
P value0.0000004
Pvalue mlog6.39794000867203
P value text
Or beta0.085
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position218503102
Reported geneIntergenic
Mapped geneTGFB2 - LOC105372924
Upstream gene id7042
Downstream gene id105372924
SNP gene ids
Upstream gene distance58483
Downstream gene distance195462
SNP risk allelers72738847-T
SNPsrs72738847
Merged0
SNP id current72738847
Contextintergenic_variant
Intergenic1
Allele frequency0.106
P value0.00000005
Pvalue mlog7.30102999566398
P value text
Or beta0.018
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264