SNP Detail For rs7258249
1.Mapping Information
Human SNP ID rs7258249
Human chromosome chr19
Human SNP position 8206837
Pig chromosome chr2
Pig SNP position 71449674
2.Annotation Information
PubMed ID22359512
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22359512
StudyGenome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.
Disease/TraitSphingolipid levels
Initial sample4,034 European ancestry individuals
Replication sampleNA
Region19p13.2
Chromosome idchr19
Chromosome position8206837
Reported geneLASS4
Mapped geneFBN3 - CERS4
Upstream gene id84467
Downstream gene id79603
SNP gene ids
Upstream gene distance57825
Downstream gene distance2492
SNP risk allelers7258249-?
SNPsrs7258249
Merged0
SNP id current7258249
Contextintron_variant
Intergenic1
Allele frequencyNR
P value1E-34
Pvalue mlog34
P value text(levels)
Or beta0
%95 Ci[0.80-3.70] % increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitsphingolipid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004622
Study accessionGCST001413
PubMed ID19798445
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19798445
StudyGenetic determinants of circulating sphingolipid concentrations in European populations.
Disease/TraitSphingolipid levels
Initial sample4,110 European ancestry individuals
Replication sampleNA
Region19p13.2
Chromosome idchr19
Chromosome position8206837
Reported geneLASS4
Mapped geneFBN3 - CERS4
Upstream gene id84467
Downstream gene id79603
SNP gene ids
Upstream gene distance57825
Downstream gene distance2492
SNP risk allelers7258249-G
SNPsrs7258249
Merged0
SNP id current7258249
Contextintron_variant
Intergenic1
Allele frequency0.48
P value2E-27
Pvalue mlog26.698970004336
P value text(SM 18:1Mol%)
Or beta0
%95 Ci[0.0007-0.001] mol % increase
PlatformIllumina [318237]
CNVN
Mapped traitsphingolipid measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004622
Study accessionGCST000493