SNP Detail For rs7255436
1.Mapping Information
Human SNP ID rs7255436
Human chromosome chr19
Human SNP position 8368312
Pig chromosome chr2
Pig SNP position 71276160
2.Annotation Information
PubMed ID20686565
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/20686565
StudyBiological, clinical and population relevance of 95 loci for blood lipids.
Disease/TraitHDL cholesterol
Initial sample99,900 European ancestry individuals
Replication sampleNA
Region19p13.2
Chromosome idchr19
Chromosome position8368312
Reported geneANGPTL4
Mapped geneANGPTL4
Upstream gene id
Downstream gene id
SNP gene ids51129
Upstream gene distance
Downstream gene distance
SNP risk allelers7255436-C
SNPsrs7255436
Merged0
SNP id current7255436
Contextintron_variant
Intergenic0
Allele frequency0.47
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta0.45
%95 Ci[0.29-0.61] mg/dL decrease
PlatformAffymetrix, Illumina, Perlegen [~ 2600000] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST000755
PubMed ID24097068
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24097068
StudyDiscovery and refinement of loci associated with lipid levels.
Disease/TraitHDL cholesterol
Initial sample94,595 European ancestry individuals
Replication sample93,982 European ancestry individuals
Region19p13.2
Chromosome idchr19
Chromosome position8368312
Reported geneANGPTL4
Mapped geneANGPTL4
Upstream gene id
Downstream gene id
SNP gene ids51129
Upstream gene distance
Downstream gene distance
SNP risk allelers7255436-C
SNPsrs7255436
Merged0
SNP id current7255436
Contextintron_variant
Intergenic0
Allele frequency0.47
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta0.032
%95 Ci[NR] unit decrease
PlatformNR [NR] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST002223