SNP Detail For rs7224000
1.Mapping Information
Human SNP ID rs7224000
Human chromosome chr17
Human SNP position 67414818
Pig chromosome chr12
Pig SNP position 14135150
2.Annotation Information
PubMed ID24503447
JournalAntivir Ther
Linkwww.ncbi.nlm.nih.gov/pubmed/24503447
StudyGenome-wide association study to characterize serum bilirubin elevations in patients with HCV treated with GS-9256, an HCV NS3 serine protease inhibitor.
Disease/TraitResponse to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels)
Initial sample176 European ancestry individuals
Replication sampleNA
Region17q24.2
Chromosome idchr17
Chromosome position67414818
Reported genePITPNC1
Mapped genePITPNC1
Upstream gene id
Downstream gene id
SNP gene ids26207
Upstream gene distance
Downstream gene distance
SNP risk allelers7224000-?
SNPsrs7224000
Merged0
SNP id current7224000
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000003
Pvalue mlog5.52287874528033
P value text
Or beta0.12
%95 Ci[NR] unit increase
PlatformIllumina [4466593]
CNVN
Mapped traitresponse to protease inhibitor, hepatitis C infection, bilirubin measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005657, http://www.ebi.ac.uk/efo/EFO_0003047, http://www.ebi.ac.uk/efo/EFO_0004570
Study accessionGCST002349