SNP Detail For rs7200786
1.Mapping Information
Human SNP ID rs7200786
Human chromosome chr16
Human SNP position 11083944
Pig chromosome JH118627-1
Pig SNP position 61243
2.Annotation Information
PubMed ID21833088
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/21833088
StudyGenetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Disease/TraitMultiple sclerosis
Initial sample9,772 European ancestry cases, 16,849 European ancestry controls
Replication sample4,218 European ancestry cases, 7,296 European ancestry controls
Region16p13.13
Chromosome idchr16
Chromosome position11083944
Reported geneCLEC16A
Mapped geneCLEC16A
Upstream gene id
Downstream gene id
SNP gene ids23274
Upstream gene distance
Downstream gene distance
SNP risk allelers7200786-A
SNPsrs7200786
Merged0
SNP id current7200786
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000000000000009
Pvalue mlog16.0457574905606
P value text
Or beta1.15
%95 Ci[1.13-1.16]
PlatformIllumina [465434]
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST001198
PubMed ID26502338
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26502338
StudyGenetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Disease/TraitSystemic lupus erythematosus
Initial sample5,201 European ancestry cases, 9,066 European ancestry controls
Replication sampleNA
Region16p13.13
Chromosome idchr16
Chromosome position11083944
Reported geneCIITA, SOCS1
Mapped geneCLEC16A
Upstream gene id
Downstream gene id
SNP gene ids23274
Upstream gene distance
Downstream gene distance
SNP risk allelers7200786-A
SNPsrs7200786
Merged0
SNP id current7200786
Contextintron_variant
Intergenic0
Allele frequency
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta1.15
%95 Ci[NR]
PlatformIllumina [> 644674] (imputed)
CNVN
Mapped traitsystemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST003156