SNP Detail For rs7194356
1.Mapping Information
Human SNP ID rs7194356
Human chromosome chr16
Human SNP position 17968279
Pig chromosome chr3
Pig SNP position 28588420
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region16p12.3
Chromosome idchr16
Chromosome position17968279
Reported geneNR
Mapped geneRPL7P47 - LOC105376750
Upstream gene id146110
Downstream gene id105376750
SNP gene ids
Upstream gene distance34934
Downstream gene distance105595
SNP risk allelers7194356-C
SNPsrs7194356
Merged0
SNP id current7194356
Contextintron_variant
Intergenic1
Allele frequency0.895432401869159
P value0.000007
Pvalue mlog5.15490195998574
P value text(IGP48)
Or beta0.2261
%95 Ci[0.13-0.32] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848