SNP Detail For rs7172432
1.Mapping Information
Human SNP ID rs7172432
Human chromosome chr15
Human SNP position 62104190
Pig chromosome chr1
Pig SNP position 121315323
2.Annotation Information
PubMed ID20818381
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20818381
StudyA genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.
Disease/TraitType 2 diabetes
Initial sample4,470 Japanese ancestry cases, 3,071 Japanese ancestry controls
Replication sample10,692 Japanese ancestry cases, 9,597 Japanese ancestry controls, 6,980 European ancestry cases, 8,615 European ancestry controls
Region15q22.2
Chromosome idchr15
Chromosome position62104190
Reported geneC2CD4B, C2CD4A
Mapped geneNPM1P47 - C2CD4B
Upstream gene id100129972
Downstream gene id388125
SNP gene ids
Upstream gene distance20791
Downstream gene distance59348
SNP risk allelers7172432-?
SNPsrs7172432
Merged0
SNP id current7172432
Contextintergenic_variant
Intergenic1
Allele frequency0.58
P value0.00000000000009
Pvalue mlog13.0457574905606
P value text
Or beta1.11
%95 Ci[1.08-1.14]
PlatformIllumina [459359]
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST000787
PubMed ID23945395
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23945395
StudyGenome-wide association study identifies three novel loci for type 2 diabetes.
Disease/TraitType 2 diabetes
Initial sample5,976 Japanese ancestry cases, 20,829 Japanese ancestry controls
Replication sample24,416 East Asian ancestry cases, 13,985 East Asian ancestry controls
Region15q22.2
Chromosome idchr15
Chromosome position62104190
Reported geneC2CD4B, C2CD4A
Mapped geneNPM1P47 - C2CD4B
Upstream gene id100129972
Downstream gene id388125
SNP gene ids
Upstream gene distance20791
Downstream gene distance59348
SNP risk allelers7172432-A
SNPsrs7172432
Merged0
SNP id current7172432
Contextintergenic_variant
Intergenic1
Allele frequency0.57
P value0.000001
Pvalue mlog6
P value text
Or beta1.11
%95 Ci[1.07-1.16]
PlatformIllumina [6209637] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002128