SNP Detail For rs71559680
1.Mapping Information
Human SNP ID rs71559680
Human chromosome chr6
Human SNP position 21430497
Pig chromosome chr7
Pig SNP position 17648328
2.Annotation Information
PubMed ID26192919
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26192919
StudyAssociation analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Disease/TraitCrohn__s disease
Initial sample5,956 European ancestry cases, 14,927 European ancestry controls
Replication sample14,594 European ancestry cases, 26,715 European ancestry controls, 151 Iranian ancestry cases, 342 Iranian ancestry controls, 184 Indian ancestry cases, 990 Indian ancestry controls, 1,690 East Asian ancestry cases, 3,719 East Asian ancestry controls
Region6p22.3
Chromosome idchr6
Chromosome position21430497
Reported geneNR
Mapped geneCDKAL1 - LINC00581
Upstream gene id54901
Downstream gene id100874531
SNP gene ids
Upstream gene distance198093
Downstream gene distance55564
SNP risk allelers71559680-A
SNPsrs71559680
Merged
SNP id current71559680
Contextintergenic_variant
Intergenic1
Allele frequency0.53
P value0.000000000000002
Pvalue mlog14.698970004336
P value text(EA)
Or beta1.1003201
%95 Ci
PlatformAffymetrix, Illumina [~ 9000000] (imputed)
CNVN
Mapped traitCrohn__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000384
Study accessionGCST003044
PubMed ID26192919
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26192919
StudyAssociation analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Disease/TraitInflammatory bowel disease
Initial sample12,882 European ancestry cases, 21,770 European ancestry controls
Replication sample25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls
Region6p22.3
Chromosome idchr6
Chromosome position21430497
Reported geneNR
Mapped geneCDKAL1 - LINC00581
Upstream gene id54901
Downstream gene id100874531
SNP gene ids
Upstream gene distance198093
Downstream gene distance55564
SNP risk allelers71559680-G
SNPsrs71559680
Merged
SNP id current71559680
Contextintergenic_variant
Intergenic1
Allele frequency0.53
P value0.0000000002
Pvalue mlog9.69897000433601
P value text(EA)
Or beta1.0647465
%95 Ci
PlatformAffymetrix, Illumina [~ 9000000] (imputed)
CNVN
Mapped traitinflammatory bowel disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003767
Study accessionGCST003043