Human SNP ID | rs7108738 |
---|---|
Human chromosome | chr11 |
Human SNP position | 15688538 |
Pig chromosome | chr2 |
Pig SNP position | 46550837 |
PubMed ID | 22504420 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22504420 |
Study | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. |
Disease/Trait | Bone mineral density |
Initial sample | Up to 32,961 European and East Asian ancestry individuals |
Replication sample | Up to 50,933 European and East Asian ancestry individuals |
Region | 11p15.2 |
Chromosome id | chr11 |
Chromosome position | 15688538 |
Reported gene | SOX6 |
Mapped gene | LOC102724957 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 102724957 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7108738-T |
SNPs | rs7108738 |
Merged | 0 |
SNP id current | 7108738 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.83 |
P value | 1E-32 |
Pvalue mlog | 32 |
P value text | (FNBMD) |
Or beta | 0.08 |
%95 Ci | [NR] unit decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST001482 |
PubMed ID | 24249740 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24249740 |
Study | Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. |
Disease/Trait | Bone mineral density |
Initial sample | 5,833 European ancestry females, 2,639 European ancestry males, 784 Han Chinese ancestry females, 763 Han Chinese ancestry males, 712 African American females, 409 Hispanic females |
Replication sample | 7,010 European ancestry females, 3,772 European ancestry males, 2,980 East Asian ancestry females, 2,159 East Asian ancestry males |
Region | 11p15.2 |
Chromosome id | chr11 |
Chromosome position | 15688538 |
Reported gene | SOX6 |
Mapped gene | LOC102724957 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 102724957 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs7108738-? |
SNPs | rs7108738 |
Merged | 0 |
SNP id current | 7108738 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000000000000001 |
Pvalue mlog | 15 |
P value text | (FNK) |
Or beta | |
%95 Ci | |
Platform | Affymetrix, Illumina [5842825] (imputed) |
CNV | N |
Mapped trait | bone density |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003923 |
Study accession | GCST002276 |