SNP Detail For rs7041847
1.Mapping Information
Human SNP ID rs7041847
Human chromosome chr9
Human SNP position 4287466
Pig chromosome chr1
Pig SNP position 243435001
2.Annotation Information
PubMed ID22158537
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22158537
StudyMeta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
Disease/TraitType 2 diabetes
Initial sample5,999 East Asian ancestry cases, 9,001 East Asian ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 159 Filipino ancestry cases, 1,624 Filipino ancestry controls
Replication sample18,127 East Asian ancestry cases, 17,746 East Asian ancestry controls
Region9p24.2
Chromosome idchr9
Chromosome position4287466
Reported geneGLIS3
Mapped geneGLIS3
Upstream gene id
Downstream gene id
SNP gene ids169792
Upstream gene distance
Downstream gene distance
SNP risk allelers7041847-A
SNPsrs7041847
Merged0
SNP id current7041847
Contextintron_variant
Intergenic0
Allele frequency0.41
P value0.00000000000002
Pvalue mlog13.698970004336
P value text
Or beta1.1
%95 Ci[1.07鈥?.13]
PlatformAffymetrix, Illumina [2626356] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST001351
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region9p24.2
Chromosome idchr9
Chromosome position4287466
Reported geneGLIS3
Mapped geneGLIS3
Upstream gene id
Downstream gene id
SNP gene ids169792
Upstream gene distance
Downstream gene distance
SNP risk allelers7041847-A
SNPsrs7041847
Merged0
SNP id current7041847
Contextintron_variant
Intergenic0
Allele frequency0.5
P value0.000005
Pvalue mlog5.30102999566398
P value text
Or beta1.05
%95 Ci[1.01-1.09]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352