Human SNP ID | rs704 |
---|---|
Human chromosome | chr17 |
Human SNP position | 28367840 |
Pig chromosome | chr12 |
Pig SNP position | 46563634 |
PubMed ID | 25080503 |
---|---|
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25080503 |
Study | Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. |
Disease/Trait | Osteoprotegerin levels |
Initial sample | 4,158 European ancestry males, 531 South Tyrol males, 4,253 European ancestry females, 692 South Tyrol females, 702 Han Chinese ancestry females |
Replication sample | NA |
Region | 17q11.2 |
Chromosome id | chr17 |
Chromosome position | 28367840 |
Reported gene | MIR4723, VTN, IFT20, SARM1, TNFAIP1, SLC46A1, TMEM199, SEBOX, FLJ40504, POLDIP2, TMEM97 |
Mapped gene | VTN |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7448 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs704-A |
SNPs | rs704 |
Merged | 0 |
SNP id current | 704 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.494 |
P value | 0.000000001 |
Pvalue mlog | 9 |
P value text | (Sex-combined) |
Or beta | 0.03 |
%95 Ci | [0.020-0.040] unit decrease |
Platform | Affymetrix, Illumina [up to 2544063] (imputed) |
CNV | N |
Mapped trait | osteoprotegerin measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005918 |
Study accession | GCST002546 |