SNP Detail For rs704
1.Mapping Information
Human SNP ID rs704
Human chromosome chr17
Human SNP position 28367840
Pig chromosome chr12
Pig SNP position 46563634
2.Annotation Information
PubMed ID25080503
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25080503
StudyMeta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels.
Disease/TraitOsteoprotegerin levels
Initial sample4,158 European ancestry males, 531 South Tyrol males, 4,253 European ancestry females, 692 South Tyrol females, 702 Han Chinese ancestry females
Replication sampleNA
Region17q11.2
Chromosome idchr17
Chromosome position28367840
Reported geneMIR4723, VTN, IFT20, SARM1, TNFAIP1, SLC46A1, TMEM199, SEBOX, FLJ40504, POLDIP2, TMEM97
Mapped geneVTN
Upstream gene id
Downstream gene id
SNP gene ids7448
Upstream gene distance
Downstream gene distance
SNP risk allelers704-A
SNPsrs704
Merged0
SNP id current704
Contextmissense_variant
Intergenic0
Allele frequency0.494
P value0.000000001
Pvalue mlog9
P value text(Sex-combined)
Or beta0.03
%95 Ci[0.020-0.040] unit decrease
PlatformAffymetrix, Illumina [up to 2544063] (imputed)
CNVN
Mapped traitosteoprotegerin measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005918
Study accessionGCST002546