SNP Detail For rs7034200
1.Mapping Information
Human SNP ID rs7034200
Human chromosome chr9
Human SNP position 4289050
Pig chromosome chr1
Pig SNP position 243432611
2.Annotation Information
PubMed ID20081858
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20081858
StudyNew genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Disease/TraitFasting glucose-related traits
Initial sampleup to 46,186 European ancestry individuals
Replication sampleup to 76,558 European ancestry individuals
Region9p24.2
Chromosome idchr9
Chromosome position4289050
Reported geneGLIS3
Mapped geneGLIS3
Upstream gene id
Downstream gene id
SNP gene ids169792
Upstream gene distance
Downstream gene distance
SNP risk allelers7034200-A
SNPsrs7034200
Merged0
SNP id current7034200
Contextintron_variant
Intergenic0
Allele frequency0.49
P value0.000000000001
Pvalue mlog12
P value text(FPG)
Or beta
%95 Ci
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitfasting blood glucose measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004465
Study accessionGCST000568
PubMed ID20081858
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20081858
StudyNew genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Disease/TraitFasting glucose-related traits
Initial sampleup to 46,186 European ancestry individuals
Replication sampleup to 76,558 European ancestry individuals
Region9p24.2
Chromosome idchr9
Chromosome position4289050
Reported geneGLIS3
Mapped geneGLIS3
Upstream gene id
Downstream gene id
SNP gene ids169792
Upstream gene distance
Downstream gene distance
SNP risk allelers7034200-A
SNPsrs7034200
Merged0
SNP id current7034200
Contextintron_variant
Intergenic0
Allele frequency0.49
P value0.0000000000001
Pvalue mlog13
P value text(HOMA-B)
Or beta
%95 Ci
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitHOMA-B
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004469
Study accessionGCST000568
PubMed ID22581228
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22581228
StudyA genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Disease/TraitFasting glucose-related traits (interaction with BMI)
Initial sampleUp to 58,074 European ancestry individuals
Replication sampleUp tp 38,422 European ancestry individuals
Region9p24.2
Chromosome idchr9
Chromosome position4289050
Reported geneGLIS3
Mapped geneGLIS3
Upstream gene id
Downstream gene id
SNP gene ids169792
Upstream gene distance
Downstream gene distance
SNP risk allelers7034200-?
SNPsrs7034200
Merged0
SNP id current7034200
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000007
Pvalue mlog6.15490195998574
P value text
Or beta
%95 Ci
PlatformAffymetrix, Illumina [~ 2400000] (imputed)
CNVN
Mapped traitbody mass index, fasting blood glucose measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004340, http://www.ebi.ac.uk/efo/EFO_0004465
Study accessionGCST001527