Human SNP ID | rs6993449 |
---|---|
Human chromosome | chr8 |
Human SNP position | 107269199 |
Pig chromosome | chr4 |
Pig SNP position | 32735958 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 8q23.1 |
Chromosome id | chr8 |
Chromosome position | 107269199 |
Reported gene | NR |
Mapped gene | ANGPT1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 284 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6993449-C |
SNPs | rs6993449 |
Merged | 0 |
SNP id current | 6993449 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.650415290106952 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | (IGP28) |
Or beta | 0.1528 |
%95 Ci | [0.088-0.217] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |