SNP Detail For rs6993449
1.Mapping Information
Human SNP ID rs6993449
Human chromosome chr8
Human SNP position 107269199
Pig chromosome chr4
Pig SNP position 32735958
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region8q23.1
Chromosome idchr8
Chromosome position107269199
Reported geneNR
Mapped geneANGPT1
Upstream gene id
Downstream gene id
SNP gene ids284
Upstream gene distance
Downstream gene distance
SNP risk allelers6993449-C
SNPsrs6993449
Merged0
SNP id current6993449
Contextintron_variant
Intergenic0
Allele frequency0.650415290106952
P value0.000003
Pvalue mlog5.52287874528033
P value text(IGP28)
Or beta0.1528
%95 Ci[0.088-0.217] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848