Human SNP ID | rs6920220 |
---|---|
Human chromosome | chr6 |
Human SNP position | 137685367 |
Pig chromosome | chr1 |
Pig SNP position | 30012057 |
PubMed ID | 17982456 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/17982456 |
Study | Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 397 European ancestry cases, 1,211 controls |
Replication sample | 1,408 cases, 2,426 controls, 875 European ancestry cases, 832 European ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | TNFAIP3, OLIG3 |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-? |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.2 |
P value | 0.0000001 |
Pvalue mlog | 7 |
P value text | |
Or beta | 1.22 |
%95 Ci | [NR] |
Platform | Affymetrix [79853] |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST000122 |
PubMed ID | 18794853 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18794853 |
Study | Common variants at CD40 and other loci confer risk of rheumatoid arthritis. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 3,393 European ancestry cases, 12,460 European ancestry controls |
Replication sample | 3,929 European ancestry cases, 5,807 European ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | TNFIP3, OLIG3 |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-? |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.22 |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | |
Or beta | 1.24 |
%95 Ci | [1.16-1.32] |
Platform | Affymetrix, Illumina [at least 315971] (imputed) |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST000232 |
PubMed ID | 21297633 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21297633 |
Study | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. |
Disease/Trait | Ulcerative colitis |
Initial sample | 6,687 European ancestry cases, 19,718 European ancestry controls |
Replication sample | 9,628 European ancestry cases, 12,917 European ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | intergenic |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-A |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.21 |
P value | 0.00000000000000008 |
Pvalue mlog | 16.096910013008 |
P value text | |
Or beta | 1.14 |
%95 Ci | [1.09-1.20] |
Platform | Affymetrix, Illumina [~ 1100000] (imputed) |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST000964 |
PubMed ID | 20453842 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20453842 |
Study | Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 5,539 European ancestry cases, 20,169 European ancestry controls |
Replication sample | 6,768 European ancestry cases, 8,806 European ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | TNFAIP3 |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-A |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.22 |
P value | 0.0000000000009 |
Pvalue mlog | 12.0457574905606 |
P value text | |
Or beta | 1.22 |
%95 Ci | [1.16-1.29] |
Platform | Affymetrix, Illumina [~ 2716259] (imputed) |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST000679 |
PubMed ID | 24449572 |
Journal | Arthritis Rheumatol |
Link | www.ncbi.nlm.nih.gov/pubmed/24449572 |
Study | Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 3,034 European ancestry cases, 5,271 European ancestry controls |
Replication sample | 4,726 European ancestry cases, 2,625 European ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | TNFAIP3 |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-? |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | |
Or beta | 1.23 |
%95 Ci | [1.14-1.32] |
Platform | Affymetrix, Illumina [1831729] (imputed) |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST002323 |
PubMed ID | 23128233 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/23128233 |
Study | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. |
Disease/Trait | Inflammatory bowel disease |
Initial sample | 12,924 European ancestry cases, 21,442 European ancestry controls |
Replication sample | 25,683 European ancestry cases, 17,015 European ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | TNFAIP3 |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-A |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.206 |
P value | 1E-21 |
Pvalue mlog | 21 |
P value text | |
Or beta | 1.102 |
%95 Ci | [1.064-1.141] |
Platform | Affymetrix, Illumina [1230000] (imputed) |
CNV | N |
Mapped trait | inflammatory bowel disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003767 |
Study accession | GCST001725 |
PubMed ID | 26192919 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26192919 |
Study | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. |
Disease/Trait | Ulcerative colitis |
Initial sample | 6,968 European ancestry cases, 20,464 European ancestry controls |
Replication sample | 10,679 European ancestry cases, 26,715 European ancestry controls, 397 Iranian ancestry cases, 342 Iranian ancestry controls, 1,239 Indian ancestry cases, 990 Indian ancestry controls, 1,134 East Asian ancestry cases, 3,719 East Asian ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | NR |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-A |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.2086 |
P value | 5E-22 |
Pvalue mlog | 21.3010299956639 |
P value text | (EA) |
Or beta | 1.1582799 |
%95 Ci | [1.13-1.19] |
Platform | Affymetrix, Illumina [~ 9000000] (imputed) |
CNV | N |
Mapped trait | ulcerative colitis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000729 |
Study accession | GCST003045 |
PubMed ID | 26192919 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26192919 |
Study | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. |
Disease/Trait | Inflammatory bowel disease |
Initial sample | 12,882 European ancestry cases, 21,770 European ancestry controls |
Replication sample | 25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137685367 |
Reported gene | NR |
Mapped gene | LOC102723649 - LOC442263 |
Upstream gene id | 102723649 |
Downstream gene id | 442263 |
SNP gene ids | |
Upstream gene distance | 10813 |
Downstream gene distance | 20456 |
SNP risk allele | rs6920220-A |
SNPs | rs6920220 |
Merged | 0 |
SNP id current | 6920220 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.2086 |
P value | 0.00000000000001 |
Pvalue mlog | 14 |
P value text | (EA) |
Or beta | 1.0993968 |
%95 Ci | [1.08-1.12] |
Platform | Affymetrix, Illumina [~ 9000000] (imputed) |
CNV | N |
Mapped trait | inflammatory bowel disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003767 |
Study accession | GCST003043 |