SNP Detail For rs6906021
1.Mapping Information
Human SNP ID rs6906021
Human chromosome chr6
Human SNP position 32658534
Pig chromosome chr7
Pig SNP position 29179710
2.Annotation Information
PubMed ID23817571
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23817571
StudyMeta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.
Disease/TraitAllergic sensitization
Initial sample5,789 European ancestry cases, 10,056 European ancestry controls
Replication sample6,114 European ancestry cases, 9,920 European ancestry controls
Region6p21.32
Chromosome idchr6
Chromosome position32658534
Reported geneHLA-DQB1, HLA-DQA1
Mapped geneHLA-DQA1 - HLA-DQB1
Upstream gene id3117
Downstream gene id3119
SNP gene ids
Upstream gene distance3760
Downstream gene distance930
SNP risk allelers6906021-C
SNPsrs6906021
Merged0
SNP id current6906021
Contextupstream_gene_variant
Intergenic1
Allele frequency0.45
P value0.000000000002
Pvalue mlog11.698970004336
P value text
Or beta1.15
%95 Ci[1.11-1.2]
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitallergic sensitization measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005298
Study accessionGCST002084
PubMed ID23817569
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23817569
StudyA genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
Disease/TraitSelf-reported allergy
Initial sample53,862 European ancestry individuals
Replication sampleNA
Region6p21.32
Chromosome idchr6
Chromosome position32658534
Reported geneHLA-DQB1, HLA-DQA1
Mapped geneHLA-DQA1 - HLA-DQB1
Upstream gene id3117
Downstream gene id3119
SNP gene ids
Upstream gene distance3760
Downstream gene distance930
SNP risk allelers6906021-C
SNPsrs6906021
Merged0
SNP id current6906021
Contextupstream_gene_variant
Intergenic1
Allele frequency0.4749
P value0.000000000000007
Pvalue mlog14.1549019599857
P value text
Or beta0.0945
%95 Ci[0.071-0.118] unit increase
PlatformIllumina [2400000] (imputed)
CNVN
Mapped traitallergy
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003785
Study accessionGCST002083