SNP Detail For rs6903961
1.Mapping Information
Human SNP ID rs6903961
Human chromosome chr6
Human SNP position 139832274
Pig chromosome chr1
Pig SNP position 27880856
2.Annotation Information
PubMed ID25089948
JournalPharmacogenet Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/25089948
StudyAncestry and other genetic associations with plasma PCSK9 response to simvastatin.
Disease/TraitResponse to simvastatin treatment (PCSK9 protein level change)
Initial sample562 European ancestry individuals
Replication sample287 African American individuals
Region6q24.1
Chromosome idchr6
Chromosome position139832274
Reported geneLOC100132735
Mapped geneLOC100132735
Upstream gene id
Downstream gene id
SNP gene ids100132735
Upstream gene distance
Downstream gene distance
SNP risk allelers6903961-A
SNPsrs6903961
Merged0
SNP id current6903961
Contextintergenic_variant
Intergenic0
Allele frequency0.167
P value0.000009
Pvalue mlog5.04575749056067
P value text(EA)
Or beta0.111
%95 Ci[NR] unit decrease
PlatformIllumina [570422]
CNVN
Mapped traitresponse to simvastatin, PCSK9 protein measurement
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_1903491, http://www.ebi.ac.uk/efo/EFO_0006899
Study accessionGCST002642