Human SNP ID | rs6903961 |
---|---|
Human chromosome | chr6 |
Human SNP position | 139832274 |
Pig chromosome | chr1 |
Pig SNP position | 27880856 |
PubMed ID | 25089948 |
---|---|
Journal | Pharmacogenet Genomics |
Link | www.ncbi.nlm.nih.gov/pubmed/25089948 |
Study | Ancestry and other genetic associations with plasma PCSK9 response to simvastatin. |
Disease/Trait | Response to simvastatin treatment (PCSK9 protein level change) |
Initial sample | 562 European ancestry individuals |
Replication sample | 287 African American individuals |
Region | 6q24.1 |
Chromosome id | chr6 |
Chromosome position | 139832274 |
Reported gene | LOC100132735 |
Mapped gene | LOC100132735 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 100132735 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6903961-A |
SNPs | rs6903961 |
Merged | 0 |
SNP id current | 6903961 |
Context | intergenic_variant |
Intergenic | 0 |
Allele frequency | 0.167 |
P value | 0.000009 |
Pvalue mlog | 5.04575749056067 |
P value text | (EA) |
Or beta | 0.111 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [570422] |
CNV | N |
Mapped trait | response to simvastatin, PCSK9 protein measurement |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_1903491, http://www.ebi.ac.uk/efo/EFO_0006899 |
Study accession | GCST002642 |