SNP Detail For rs6870564
1.Mapping Information
Human SNP ID rs6870564
Human chromosome chr5
Human SNP position 17002976
Pig chromosome chr16
Pig SNP position 6635981
2.Annotation Information
PubMed ID23400010
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/23400010
StudyGenome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
Disease/TraitThiazide-induced adverse metabolic effects in hypertensive patients
Initial sample425 European ancestry cases, 342 African American cases
Replication sampleNA
Region5p15.1
Chromosome idchr5
Chromosome position17002976
Reported geneMYO10
Mapped geneMYO10 - LOC285696
Upstream gene id4651
Downstream gene id285696
SNP gene ids
Upstream gene distance66700
Downstream gene distance127052
SNP risk allelers6870564-A
SNPsrs6870564
Merged0
SNP id current6870564
Contextintergenic_variant
Intergenic1
Allele frequency0.13
P value0.000004
Pvalue mlog5.39794000867203
P value text(EA-glucose response)
Or beta3.84
%95 Ci[2.21-5.47] mg/dL increase
PlatformAffymetrix, Illumina [> 2000000] (imputed)
CNVN
Mapped traitresponse to hydrochlorothiazide, fasting blood glucose measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005202, http://www.ebi.ac.uk/efo/EFO_0004465
Study accessionGCST001859