Human SNP ID | rs6853847 |
---|---|
Human chromosome | chr4 |
Human SNP position | 91996064 |
Pig chromosome | chr8 |
Pig SNP position | 136543608 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 91996064 |
Reported gene | NR |
Mapped gene | CCSER1 - PMPCAP1 |
Upstream gene id | 401145 |
Downstream gene id | 133083 |
SNP gene ids | |
Upstream gene distance | 393845 |
Downstream gene distance | 185892 |
SNP risk allele | rs6853847-C |
SNPs | rs6853847 |
Merged | 0 |
SNP id current | 6853847 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.0304513777282851 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP24) |
Or beta | 0.4788 |
%95 Ci | [0.28-0.67] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 4q22.1 |
Chromosome id | chr4 |
Chromosome position | 91996064 |
Reported gene | NR |
Mapped gene | CCSER1 - PMPCAP1 |
Upstream gene id | 401145 |
Downstream gene id | 133083 |
SNP gene ids | |
Upstream gene distance | 393845 |
Downstream gene distance | 185892 |
SNP risk allele | rs6853847-C |
SNPs | rs6853847 |
Merged | 0 |
SNP id current | 6853847 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.0304378588601959 |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (IGP26) |
Or beta | 0.4557 |
%95 Ci | [0.26-0.65] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |