Human SNP ID | rs6843082 |
---|---|
Human chromosome | chr4 |
Human SNP position | 110796911 |
Pig chromosome | chr8 |
Pig SNP position | 119590536 |
PubMed ID | 20173747 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20173747 |
Study | Common variants in KCNN3 are associated with lone atrial fibrillation. |
Disease/Trait | Atrial fibrillation |
Initial sample | 1,335 European ancestry cases, 12,844 European ancestry controls |
Replication sample | 1,164 European ancestry cases, 3,607 European ancestry controls |
Region | 4q25 |
Chromosome id | chr4 |
Chromosome position | 110796911 |
Reported gene | PITX2 |
Mapped gene | PITX2 - MIR297 |
Upstream gene id | 5308 |
Downstream gene id | 100126354 |
SNP gene ids | |
Upstream gene distance | 154788 |
Downstream gene distance | 63671 |
SNP risk allele | rs6843082-G |
SNPs | rs6843082 |
Merged | 0 |
SNP id current | 6843082 |
Context | non_coding_transcript_exon_variant |
Intergenic | 1 |
Allele frequency | 0.26 |
P value | 3E-28 |
Pvalue mlog | 27.5228787452803 |
P value text | |
Or beta | 2.03 |
%95 Ci | [1.79-2.30] |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | atrial fibrillation |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000275 |
Study accession | GCST000602 |
PubMed ID | 23041239 |
Journal | Lancet Neurol |
Link | www.ncbi.nlm.nih.gov/pubmed/23041239 |
Study | Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. |
Disease/Trait | Stroke (ischemic) |
Initial sample | 12,389 European ancestry cases, 62,004 European ancestry controls |
Replication sample | 1,322 Pakistani ancestry cases, 1,143 Pakistani ancestry controls, 12,025 European ancestry cases, 27,940 European ancestry controls |
Region | 4q25 |
Chromosome id | chr4 |
Chromosome position | 110796911 |
Reported gene | PITX2 |
Mapped gene | PITX2 - MIR297 |
Upstream gene id | 5308 |
Downstream gene id | 100126354 |
SNP gene ids | |
Upstream gene distance | 154788 |
Downstream gene distance | 63671 |
SNP risk allele | rs6843082-G |
SNPs | rs6843082 |
Merged | 0 |
SNP id current | 6843082 |
Context | non_coding_transcript_exon_variant |
Intergenic | 1 |
Allele frequency | 0.21 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | (IS) |
Or beta | 1.11 |
%95 Ci | [1.06-1.15] |
Platform | Affymetrix, Illumina [NR] (imputed) |
CNV | N |
Mapped trait | stroke |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000712 |
Study accession | GCST001706 |
PubMed ID | 23041239 |
Journal | Lancet Neurol |
Link | www.ncbi.nlm.nih.gov/pubmed/23041239 |
Study | Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. |
Disease/Trait | Stroke (ischemic) |
Initial sample | 12,389 European ancestry cases, 62,004 European ancestry controls |
Replication sample | 1,322 Pakistani ancestry cases, 1,143 Pakistani ancestry controls, 12,025 European ancestry cases, 27,940 European ancestry controls |
Region | 4q25 |
Chromosome id | chr4 |
Chromosome position | 110796911 |
Reported gene | PITX2 |
Mapped gene | PITX2 - MIR297 |
Upstream gene id | 5308 |
Downstream gene id | 100126354 |
SNP gene ids | |
Upstream gene distance | 154788 |
Downstream gene distance | 63671 |
SNP risk allele | rs6843082-G |
SNPs | rs6843082 |
Merged | 0 |
SNP id current | 6843082 |
Context | non_coding_transcript_exon_variant |
Intergenic | 1 |
Allele frequency | 0.21 |
P value | 0.0000000000000003 |
Pvalue mlog | 15.5228787452803 |
P value text | (CS) |
Or beta | 1.36 |
%95 Ci | [1.27-1.47] |
Platform | Affymetrix, Illumina [NR] (imputed) |
CNV | N |
Mapped trait | stroke |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000712 |
Study accession | GCST001706 |