Human SNP ID | rs6822844 |
---|---|
Human chromosome | chr4 |
Human SNP position | 122588266 |
Pig chromosome | chr8 |
Pig SNP position | 108715385 |
PubMed ID | 17558408 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/17558408 |
Study | A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. |
Disease/Trait | Celiac disease |
Initial sample | 778 European ancestry cases, 1,422 European ancestry controls |
Replication sample | 991 European ancestry cases, 1,489 European ancestry controls |
Region | 4q27 |
Chromosome id | chr4 |
Chromosome position | 122588266 |
Reported gene | IL2, TENR, KIAA1109, IL21 |
Mapped gene | IL2 - IL21 |
Upstream gene id | 3558 |
Downstream gene id | 59067 |
SNP gene ids | |
Upstream gene distance | 131771 |
Downstream gene distance | 24362 |
SNP risk allele | rs6822844-G |
SNPs | rs6822844 |
Merged | 0 |
SNP id current | 6822844 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.82 |
P value | 0.00000000000001 |
Pvalue mlog | 14 |
P value text | |
Or beta | 1.59 |
%95 Ci | [1.41-1.75] |
Platform | Illumina [310605] |
CNV | N |
Mapped trait | celiac disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001060 |
Study accession | GCST000048 |
PubMed ID | 18311140 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18311140 |
Study | Newly identified genetic risk variants for celiac disease related to the immune response. |
Disease/Trait | Celiac disease |
Initial sample | 767 European ancestry cases, 1,422 European ancestry controls |
Replication sample | 1,643 European ancestry cases, 3,406 European ancestry controls |
Region | 4q27 |
Chromosome id | chr4 |
Chromosome position | 122588266 |
Reported gene | IL2, ADAD1, KIAA1109, IL21 |
Mapped gene | IL2 - IL21 |
Upstream gene id | 3558 |
Downstream gene id | 59067 |
SNP gene ids | |
Upstream gene distance | 131771 |
Downstream gene distance | 24362 |
SNP risk allele | rs6822844-C |
SNPs | rs6822844 |
Merged | 0 |
SNP id current | 6822844 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.81 |
P value | 0.0000000000003 |
Pvalue mlog | 12.5228787452803 |
P value text | |
Or beta | 1.44 |
%95 Ci | [1.30-1.58] |
Platform | Illumina [310605] |
CNV | N |
Mapped trait | celiac disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001060 |
Study accession | GCST000157 |