SNP Detail For rs6822844
1.Mapping Information
Human SNP ID rs6822844
Human chromosome chr4
Human SNP position 122588266
Pig chromosome chr8
Pig SNP position 108715385
2.Annotation Information
PubMed ID17558408
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/17558408
StudyA genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
Disease/TraitCeliac disease
Initial sample778 European ancestry cases, 1,422 European ancestry controls
Replication sample991 European ancestry cases, 1,489 European ancestry controls
Region4q27
Chromosome idchr4
Chromosome position122588266
Reported geneIL2, TENR, KIAA1109, IL21
Mapped geneIL2 - IL21
Upstream gene id3558
Downstream gene id59067
SNP gene ids
Upstream gene distance131771
Downstream gene distance24362
SNP risk allelers6822844-G
SNPsrs6822844
Merged0
SNP id current6822844
Contextintergenic_variant
Intergenic1
Allele frequency0.82
P value0.00000000000001
Pvalue mlog14
P value text
Or beta1.59
%95 Ci[1.41-1.75]
PlatformIllumina [310605]
CNVN
Mapped traitceliac disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001060
Study accessionGCST000048
PubMed ID18311140
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/18311140
StudyNewly identified genetic risk variants for celiac disease related to the immune response.
Disease/TraitCeliac disease
Initial sample767 European ancestry cases, 1,422 European ancestry controls
Replication sample1,643 European ancestry cases, 3,406 European ancestry controls
Region4q27
Chromosome idchr4
Chromosome position122588266
Reported geneIL2, ADAD1, KIAA1109, IL21
Mapped geneIL2 - IL21
Upstream gene id3558
Downstream gene id59067
SNP gene ids
Upstream gene distance131771
Downstream gene distance24362
SNP risk allelers6822844-C
SNPsrs6822844
Merged0
SNP id current6822844
Contextintergenic_variant
Intergenic1
Allele frequency0.81
P value0.0000000000003
Pvalue mlog12.5228787452803
P value text
Or beta1.44
%95 Ci[1.30-1.58]
PlatformIllumina [310605]
CNVN
Mapped traitceliac disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001060
Study accessionGCST000157