SNP Detail For rs6812849
1.Mapping Information
Human SNP ID rs6812849
Human chromosome chr4
Human SNP position 165951384
Pig chromosome chr8
Pig SNP position 44939087
2.Annotation Information
PubMed ID23726511
JournalBiol Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/23726511
StudyGenome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
Disease/TraitPost-traumatic stress disorder (asjusted for relatedness)
Initial sampleup to 308 European ancestry cases, up to 1,538 European ancestry controls, up to 456 African American cases, up to 2,936 African American controls
Replication sampleNA
Region4q32.3
Chromosome idchr4
Chromosome position165951384
Reported geneTLL1
Mapped geneTLL1
Upstream gene id
Downstream gene id
SNP gene ids7092
Upstream gene distance
Downstream gene distance
SNP risk allelers6812849-?
SNPsrs6812849
Merged0
SNP id current6812849
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000001
Pvalue mlog7
P value text(Whole cohort; EA)
Or beta
%95 Ci
PlatformIllumina [up to 871502]
CNVN
Mapped traitpost-traumatic stress disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001358
Study accessionGCST002037
PubMed ID23726511
JournalBiol Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/23726511
StudyGenome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
Disease/TraitPost-traumatic stress disorder (asjusted for relatedness)
Initial sampleup to 308 European ancestry cases, up to 1,538 European ancestry controls, up to 456 African American cases, up to 2,936 African American controls
Replication sampleNA
Region4q32.3
Chromosome idchr4
Chromosome position165951384
Reported geneTLL1
Mapped geneTLL1
Upstream gene id
Downstream gene id
SNP gene ids7092
Upstream gene distance
Downstream gene distance
SNP risk allelers6812849-?
SNPsrs6812849
Merged0
SNP id current6812849
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000005
Pvalue mlog6.30102999566398
P value text(Trauma exposed controls; EA)
Or beta
%95 Ci
PlatformIllumina [up to 871502]
CNVN
Mapped traitpost-traumatic stress disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001358
Study accessionGCST002037
PubMed ID23726511
JournalBiol Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/23726511
StudyGenome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
Disease/TraitPost-traumatic stress disorder
Initial sample300 European ancestry cases, up to 1,538 European ancestry controls, 444 African American cases, up to 2,936 African American controls
Replication sample207 European ancestry cases, up to 1,692 European ancestry controls, 89 African American cases, up to 655 African American controls
Region4q32.3
Chromosome idchr4
Chromosome position165951384
Reported geneTLL1
Mapped geneTLL1
Upstream gene id
Downstream gene id
SNP gene ids7092
Upstream gene distance
Downstream gene distance
SNP risk allelers6812849-?
SNPsrs6812849
Merged0
SNP id current6812849
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000003
Pvalue mlog8.52287874528033
P value text(Whole cohort; EA)
Or beta
%95 Ci
PlatformIllumina [up to 871502]
CNVN
Mapped traitpost-traumatic stress disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001358
Study accessionGCST002038
PubMed ID23726511
JournalBiol Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/23726511
StudyGenome-wide association study identifies new susceptibility loci for posttraumatic stress disorder.
Disease/TraitPost-traumatic stress disorder
Initial sample300 European ancestry cases, up to 1,538 European ancestry controls, 444 African American cases, up to 2,936 African American controls
Replication sample207 European ancestry cases, up to 1,692 European ancestry controls, 89 African American cases, up to 655 African American controls
Region4q32.3
Chromosome idchr4
Chromosome position165951384
Reported geneTLL1
Mapped geneTLL1
Upstream gene id
Downstream gene id
SNP gene ids7092
Upstream gene distance
Downstream gene distance
SNP risk allelers6812849-?
SNPsrs6812849
Merged0
SNP id current6812849
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text(Trauma Exposed controls; EA)
Or beta
%95 Ci
PlatformIllumina [up to 871502]
CNVN
Mapped traitpost-traumatic stress disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001358
Study accessionGCST002038