Human SNP ID | rs6754459 |
---|---|
Human chromosome | chr2 |
Human SNP position | 3659833 |
Pig chromosome | chr3 |
Pig SNP position | 140558921 |
PubMed ID | 24792382 |
---|---|
Journal | Clin Chim Acta |
Link | www.ncbi.nlm.nih.gov/pubmed/24792382 |
Study | Genome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid. |
Disease/Trait | Response to inhaled corticosteroid treatment in asthma (percentage change of FEV1) |
Initial sample | 189 Korean ancestry cases |
Replication sample | NA |
Region | 2p25.3 |
Chromosome id | chr2;2;2;2;2;2;2;2;2;2;2;2 |
Chromosome position | 3655451;3666539;3659032;3650781;3653746;3661518;3657240;3659833;3655143;3667425;3666068;3666671 |
Reported gene | ALLC |
Mapped gene | COLEC11 - ALLC; ALLC; ALLC; COLEC11 - ALLC; COLEC11 - ALLC; ALLC; COLEC11 - ALLC; ALLC; COLEC11 - ALLC; ALLC; ALLC; ALLC |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs17445240-G; rs10173297-A; rs13384889-C; rs13031619-G; rs4849975-G; rs1965732-G; rs13418767-T; rs6754459-T; rs11902059-A; rs13395090-T; rs17017879-C; rs7558370-C |
SNPs | rs17445240; rs10173297; rs13384889; rs13031619; rs4849975; rs1965732; rs13418767; rs6754459; rs11902059; rs13395090; rs17017879; rs7558370 |
Merged | 0 |
SNP id current | |
Context | upstream_gene_variant; intron_variant; intron_variant; regulatory_region_variant; upstream_gene_variant; intron_variant; upstream_gene_variant; intron_variant; upstream_gene_variant; intron_variant; intron_variant; intron_variant |
Intergenic | |
Allele frequency | 0.093 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | |
Or beta | 0.329 |
%95 Ci | [NR] unit increase |
Platform | Illumina [430487] |
CNV | N |
Mapped trait | FEV change measurement, response to corticosteroid, asthma |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005921, http://purl.obolibrary.org/obo/GO_0031960, http://www.ebi.ac.uk/efo/EFO_0000270 |
Study accession | GCST002432 |