SNP Detail For rs6754459
1.Mapping Information
Human SNP ID rs6754459
Human chromosome chr2
Human SNP position 3659833
Pig chromosome chr3
Pig SNP position 140558921
2.Annotation Information
PubMed ID24792382
JournalClin Chim Acta
Linkwww.ncbi.nlm.nih.gov/pubmed/24792382
StudyGenome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid.
Disease/TraitResponse to inhaled corticosteroid treatment in asthma (percentage change of FEV1)
Initial sample189 Korean ancestry cases
Replication sampleNA
Region2p25.3
Chromosome idchr2;2;2;2;2;2;2;2;2;2;2;2
Chromosome position3655451;3666539;3659032;3650781;3653746;3661518;3657240;3659833;3655143;3667425;3666068;3666671
Reported geneALLC
Mapped geneCOLEC11 - ALLC; ALLC; ALLC; COLEC11 - ALLC; COLEC11 - ALLC; ALLC; COLEC11 - ALLC; ALLC; COLEC11 - ALLC; ALLC; ALLC; ALLC
Upstream gene id
Downstream gene id
SNP gene ids
Upstream gene distance
Downstream gene distance
SNP risk allelers17445240-G; rs10173297-A; rs13384889-C; rs13031619-G; rs4849975-G; rs1965732-G; rs13418767-T; rs6754459-T; rs11902059-A; rs13395090-T; rs17017879-C; rs7558370-C
SNPsrs17445240; rs10173297; rs13384889; rs13031619; rs4849975; rs1965732; rs13418767; rs6754459; rs11902059; rs13395090; rs17017879; rs7558370
Merged0
SNP id current
Contextupstream_gene_variant; intron_variant; intron_variant; regulatory_region_variant; upstream_gene_variant; intron_variant; upstream_gene_variant; intron_variant; upstream_gene_variant; intron_variant; intron_variant; intron_variant
Intergenic
Allele frequency0.093
P value0.000004
Pvalue mlog5.39794000867203
P value text
Or beta0.329
%95 Ci[NR] unit increase
PlatformIllumina [430487]
CNVN
Mapped traitFEV change measurement, response to corticosteroid, asthma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005921, http://purl.obolibrary.org/obo/GO_0031960, http://www.ebi.ac.uk/efo/EFO_0000270
Study accessionGCST002432