Human SNP ID | rs6687262 |
---|---|
Human chromosome | chr1 |
Human SNP position | 79043424 |
Pig chromosome | chr6 |
Pig SNP position | 124494671 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 1p31.1 |
Chromosome id | chr1 |
Chromosome position | 79043424 |
Reported gene | NR |
Mapped gene | ADGRL4 - LOC105378810 |
Upstream gene id | 64123 |
Downstream gene id | 105378810 |
SNP gene ids | |
Upstream gene distance | 36614 |
Downstream gene distance | 226980 |
SNP risk allele | rs6687262-C |
SNPs | rs6687262 |
Merged | 0 |
SNP id current | 6687262 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.552969396260018 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP31) |
Or beta | 0.1461 |
%95 Ci | [0.085-0.207] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 1p31.1 |
Chromosome id | chr1 |
Chromosome position | 79043424 |
Reported gene | NR |
Mapped gene | ADGRL4 - LOC105378810 |
Upstream gene id | 64123 |
Downstream gene id | 105378810 |
SNP gene ids | |
Upstream gene distance | 36614 |
Downstream gene distance | 226980 |
SNP risk allele | rs6687262-C |
SNPs | rs6687262 |
Merged | 0 |
SNP id current | 6687262 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.553310385988398 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | (IGP37) |
Or beta | 0.1576 |
%95 Ci | [0.097-0.219] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 1p31.1 |
Chromosome id | chr1 |
Chromosome position | 79043424 |
Reported gene | NR |
Mapped gene | ADGRL4 - LOC105378810 |
Upstream gene id | 64123 |
Downstream gene id | 105378810 |
SNP gene ids | |
Upstream gene distance | 36614 |
Downstream gene distance | 226980 |
SNP risk allele | rs6687262-C |
SNPs | rs6687262 |
Merged | 0 |
SNP id current | 6687262 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.553040158270174 |
P value | 0.0000005 |
Pvalue mlog | 6.30102999566398 |
P value text | (IGP38) |
Or beta | 0.1567 |
%95 Ci | [0.096-0.218] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |