Human SNP ID | rs6570507 |
---|---|
Human chromosome | chr6 |
Human SNP position | 142358435 |
Pig chromosome | chr1 |
Pig SNP position | 25348996 |
PubMed ID | 19343178 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19343178 |
Study | Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. |
Disease/Trait | Height |
Initial sample | 12,611 European ancestry individuals |
Replication sample | 7,187 European ancestry individuals |
Region | 6q24.2 |
Chromosome id | chr6 |
Chromosome position | 142358435 |
Reported gene | GPR126 |
Mapped gene | ADGRG6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57211 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6570507-? |
SNPs | rs6570507 |
Merged | 0 |
SNP id current | 6570507 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.42 |
P value | 0.00000000004 |
Pvalue mlog | 10.397940008672 |
P value text | |
Or beta | 0.08 |
%95 Ci | [0.06-0.10] s.d. decrease |
Platform | Illumina [229216] |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST000372 |
PubMed ID | 20397748 |
Journal | Twin Res Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20397748 |
Study | Genome-wide association study of height and body mass index in Australian twin families. |
Disease/Trait | Height |
Initial sample | 11,536 European ancestry individuals |
Replication sample | NA |
Region | 6q24.2 |
Chromosome id | chr6 |
Chromosome position | 142358435 |
Reported gene | GPR126 |
Mapped gene | ADGRG6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57211 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6570507-G |
SNPs | rs6570507 |
Merged | 0 |
SNP id current | 6570507 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.71 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | |
Or beta | 0.08 |
%95 Ci | [0.04-0.12] SD increase |
Platform | Illumina [559712] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST000644 |
PubMed ID | 23666238 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23666238 |
Study | Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis. |
Disease/Trait | Scoliosis |
Initial sample | 1,033 Japanese ancestry cases, 1,473 Japanese ancestry controls |
Replication sample | 1,529 East Asian ancestry cases, 25,675 East Asian ancestry controls, 447 European ancestry cases, 737 European ancestry controls |
Region | 6q24.2 |
Chromosome id | chr6 |
Chromosome position | 142358435 |
Reported gene | GPR126 |
Mapped gene | ADGRG6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57211 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6570507-? |
SNPs | rs6570507 |
Merged | 0 |
SNP id current | 6570507 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.43 |
P value | 0.000000000004 |
Pvalue mlog | 11.397940008672 |
P value text | (East Asian) |
Or beta | 1.26 |
%95 Ci | [1.18-1.35] |
Platform | Illumina [465762] |
CNV | N |
Mapped trait | scoliosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004273 |
Study accession | GCST002020 |
PubMed ID | 23666238 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23666238 |
Study | Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis. |
Disease/Trait | Scoliosis |
Initial sample | 1,033 Japanese ancestry cases, 1,473 Japanese ancestry controls |
Replication sample | 1,529 East Asian ancestry cases, 25,675 East Asian ancestry controls, 447 European ancestry cases, 737 European ancestry controls |
Region | 6q24.2 |
Chromosome id | chr6 |
Chromosome position | 142358435 |
Reported gene | GPR126 |
Mapped gene | ADGRG6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57211 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6570507-? |
SNPs | rs6570507 |
Merged | 0 |
SNP id current | 6570507 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.43 |
P value | 0.00000000000001 |
Pvalue mlog | 14 |
P value text | |
Or beta | 1.27 |
%95 Ci | [1.20-1.35] |
Platform | Illumina [465762] |
CNV | N |
Mapped trait | scoliosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004273 |
Study accession | GCST002020 |
PubMed ID | 25429064 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25429064 |
Study | Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. |
Disease/Trait | Height |
Initial sample | 36,227 East Asian ancestry individuals |
Replication sample | 57,699 East Asian ancestry individuals |
Region | 6q24.2 |
Chromosome id | chr6 |
Chromosome position | 142358435 |
Reported gene | GPR126 |
Mapped gene | ADGRG6 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57211 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6570507-A |
SNPs | rs6570507 |
Merged | 0 |
SNP id current | 6570507 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.38 |
P value | 0.00000000002 |
Pvalue mlog | 10.698970004336 |
P value text | |
Or beta | 0.032 |
%95 Ci | [0.02-0.044] unit decrease |
Platform | Affymetrix, Illumina [2704730] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST002702 |